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SMILES Brc1ccc2[nH]c-3c(CC(=O)N(Cc4ccccc4)c4ccccc-34)c2c1

InChI Key InChIKey=HMNQLGPAVMICRU-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 7307   

TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
CNRS

LigandPNGBDBM7307(5-benzyl-9-bromopaullone | 8-benzyl-14-bromo-8,18-...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+4nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5RJSPubMed
TargetCyclin-dependent kinase 5 activator 1 [99-307](Homo sapiens (Human))
CNRS

LigandPNGBDBM7307(5-benzyl-9-bromopaullone | 8-benzyl-14-bromo-8,18-...)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+5nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5RJSPubMed
TargetGlycogen synthase kinase-3 beta(Rattus norvegicus (rat))
CNRS

LigandPNGBDBM7307(5-benzyl-9-bromopaullone | 8-benzyl-14-bromo-8,18-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5RJSPubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Universität Hamburg

Curated by ChEMBL
LigandPNGBDBM7307(5-benzyl-9-bromopaullone | 8-benzyl-14-bromo-8,18-...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+4nMAssay Description:In vitro inhibitory activity against cyclin-dependent kinase 1-cyclin B (Cyclin-Dependent Kinase) harvested from starfish oocytes.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1W2RPubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Albert-Ludwigs-Universität Freiburg

Curated by ChEMBL
LigandPNGBDBM7307(5-benzyl-9-bromopaullone | 8-benzyl-14-bromo-8,18-...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human SIRT1 by radioactive deacetylase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ616PPubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Albert-Ludwigs-Universität Freiburg

Curated by ChEMBL
LigandPNGBDBM7307(5-benzyl-9-bromopaullone | 8-benzyl-14-bromo-8,18-...)copy SMILEScopy InChI
Affinity DataIC50: 4.28E+4nMAssay Description:Inhibition of human recombinant SIRT2 by fluorescent deacetylase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ616PPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Technische Universit£t Braunschweig

Curated by ChEMBL
LigandPNGBDBM7307(5-benzyl-9-bromopaullone | 8-benzyl-14-bromo-8,18-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9C1VPubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Albert-Ludwigs-Universität Freiburg

Curated by ChEMBL
LigandPNGBDBM7307(5-benzyl-9-bromopaullone | 8-benzyl-14-bromo-8,18-...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human SIRT1 by fluorescent deacetylase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ616PPubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Albert-Ludwigs-Universität Freiburg

Curated by ChEMBL
LigandPNGBDBM7307(5-benzyl-9-bromopaullone | 8-benzyl-14-bromo-8,18-...)copy SMILEScopy InChI
Affinity DataIC50: 4.28E+4nMAssay Description:Inhibition of human recombinant SIRT2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ616PPubMed
LigandPNGBDBM7307(5-benzyl-9-bromopaullone | 8-benzyl-14-bromo-8,18-...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of CDK1/cyclin B expressed in M phase starfish oocyteMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9C1VPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Technische Universit£t Braunschweig

Curated by ChEMBL
LigandPNGBDBM7307(5-benzyl-9-bromopaullone | 8-benzyl-14-bromo-8,18-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GSK3-beta expressed in insect Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9C1VPubMed
TargetMalate dehydrogenase, mitochondrial(Homo sapiens (Human))
Technische Universit£t Braunschweig

Curated by ChEMBL
LigandPNGBDBM7307(5-benzyl-9-bromopaullone | 8-benzyl-14-bromo-8,18-...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of mitochondrial malate dehydrogenase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9C1VPubMed
LigandPNGBDBM7307(5-benzyl-9-bromopaullone | 8-benzyl-14-bromo-8,18-...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of CDK1/cyclin BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9C1VPubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Albert-Ludwigs-Universität Freiburg

Curated by ChEMBL
LigandPNGBDBM7307(5-benzyl-9-bromopaullone | 8-benzyl-14-bromo-8,18-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant SIRT2 by radioactive deacetylase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ616PPubMed