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SMILES COc1cccc(c1)C1=C(Nc2ccc(Cl)c(c2)C(O)=O)C(=O)NC1=O

InChI Key InChIKey=CKNBSSMNQGLXEA-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 8270   

TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

LigandPNGBDBM8270(2-chloro-5-{[4-(3-methoxyphenyl)-2,5-dioxo-2,5-dih...)copy SMILEScopy InChI
Affinity DataIC50: 85nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3JRCPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
University of Jordan

Curated by ChEMBL
LigandPNGBDBM8270(2-chloro-5-{[4-(3-methoxyphenyl)-2,5-dioxo-2,5-dih...)copy SMILEScopy InChI
Affinity DataIC50: 85nMAssay Description:Inhibition of recombinant GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z744CPubMed
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))TBA
LigandPNGBDBM8270(2-chloro-5-{[4-(3-methoxyphenyl)-2,5-dioxo-2,5-dih...)copy SMILEScopy InChI
Affinity DataKd:  460nMMore data for this Ligand-Target Pair
In DepthDetails
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))TBA
LigandPNGBDBM8270(2-chloro-5-{[4-(3-methoxyphenyl)-2,5-dioxo-2,5-dih...)copy SMILEScopy InChI
Affinity DataKd:  1.00E+4nMAssay Description:D3R2022More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28S4TSSPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM8270(2-chloro-5-{[4-(3-methoxyphenyl)-2,5-dioxo-2,5-dih...)copy SMILEScopy InChI
Affinity DataKd:  1.00E+4nMAssay Description:D3R2023More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q251433MPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))TBA
LigandPNGBDBM8270(2-chloro-5-{[4-(3-methoxyphenyl)-2,5-dioxo-2,5-dih...)copy SMILEScopy InChI
Affinity DataKd:  1.00E+4nMAssay Description:D3R2021More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5KHHPubMed