null
SMILES Cc1ccc2c(N)c3CCCCc3nc2c1
InChI Key InChIKey=XEAIOWJVFCHDRX-UHFFFAOYSA-N
PDB links: 4 PDB IDs contain inhibitors having a similarity of 90% to this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 8985
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The appearance of product was monitored at 412 nm for 5 min us...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against human erythrocyte acetylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 72nMAssay Description:Inhibition of human recombinant AChE assessed as reduction in cholinesterase activity using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 4.18E+4nMAssay Description:Inhibition of human GluN1a/GluN2B receptor expressed in HEK293 cells assessed as relative inhibition of glycine/glutamate-induced current measured at...More data for this Ligand-Target Pair
Affinity DataIC50: 1.71E+4nMAssay Description:Inhibition of human GluN1a/GluN2A receptor expressed in HEK293 cells assessed as inhibition of glycine/glutamate-induced current measured at -60 mV h...More data for this Ligand-Target Pair
Affinity DataIC50: 7.83E+3nMAssay Description:Inhibition of human GluN1a/GluN2B receptor expressed in HEK293 cells assessed as inhibition of glycine/glutamate-induced current measured at -60 mV h...More data for this Ligand-Target Pair
Affinity DataIC50: 9.86E+4nMAssay Description:Inhibition of human GluN1a/GluN2A receptor expressed in HEK293 cells assessed as relative inhibition of glycine/glutamate-induced current measured at...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human plasmatic BuChE assessed as reduction in cholinesterase activity by Ellman's methodMore data for this Ligand-Target Pair