null

SMILES COc1cc2CC(CNCCCCCCCNc3c4CCCCc4nc4ccccc34)C(=O)c2cc1OC

InChI Key InChIKey=LSAKEKKNQBBHNE-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 9063   

TargetAcetylcholinesterase(Bos taurus (bovine))
Neuropharma

LigandPNGBDBM9063(5,6-Dimethoxy-2-{[7-(1,2,3,4-tetrahydro-acridin-9-...)copy SMILEScopy InChI
Affinity DataIC50: 25nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73BW9PubMed
TargetCholinesterase(Homo sapiens (Human))
Laboratori de Qu�mica Farmac�utica (Unitat Associada al CSIC)

Curated by ChEMBL
LigandPNGBDBM9063(5,6-Dimethoxy-2-{[7-(1,2,3,4-tetrahydro-acridin-9-...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human serum BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76DGKPubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Neuropharma

LigandPNGBDBM9063(5,6-Dimethoxy-2-{[7-(1,2,3,4-tetrahydro-acridin-9-...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of bovine erythrocyte AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76DGKPubMed
TargetCholinesterase(Homo sapiens (Human))
Laboratori de Qu�mica Farmac�utica (Unitat Associada al CSIC)

Curated by ChEMBL
LigandPNGBDBM9063(5,6-Dimethoxy-2-{[7-(1,2,3,4-tetrahydro-acridin-9-...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73BW9PubMed