null

SMILES O[C@@H](C[C@@H](Cc1ccncc1)C(=O)N[C@@H]1[C@H](O)COc2ccccc12)CN1CCN(Cc2cc3ccccc3o2)C[C@H]1C(=O)NCC(F)(F)F

InChI Key InChIKey=DIVWCYHNQIMLLP-NKBKYVEPSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 9158   

TargetDimer of Gag-Pol polyprotein [489-587,Q496K](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM9158((2S)-4-(1-benzofuran-2-ylmethyl)-1-[(2S,4R)-2-hydr...)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMpH: 5.5 T: 2°CAssay Description:Assay of HIV protease inhibition was performed by peptide cleavage using the substrate Val-Ser-Gln-Asn-beta-naphthylalanine*Pro-Ile-Val. Products of ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K072GNPubMed
LigandPNGBDBM9158((2S)-4-(1-benzofuran-2-ylmethyl)-1-[(2S,4R)-2-hydr...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Assay of HIV protease inhibition was performed by peptide cleavage using the substrate Val-Ser-Gln-Asn-beta-naphthylalanine*Pro-Ile-Val. Products of ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K072GNPubMed
LigandPNGBDBM9158((2S)-4-(1-benzofuran-2-ylmethyl)-1-[(2S,4R)-2-hydr...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Assay of HIV protease inhibition was performed by peptide cleavage using the substrate Val-Ser-Gln-Asn-beta-naphthylalanine*Pro-Ile-Val. Products of ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K072GNPubMed