null

SMILES CCCNC(=O)c1ccc(s1)-n1c(C)cc2ccccc12

InChI Key InChIKey=OQYMMMMIAASALW-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 92604   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
Harvard Medical School

LigandPNGBDBM92604(DHOD Inhibitor, 3 | US8703811, 1)copy SMILEScopy InChI
Affinity DataIC50: 420nMAssay Description:Assay was determined using a continuous assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5MFQPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Harvard Medical School

LigandPNGBDBM92604(DHOD Inhibitor, 3 | US8703811, 1)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Assay was determined using a continuous assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5MFQPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium vivax)
Harvard Medical School

LigandPNGBDBM92604(DHOD Inhibitor, 3 | US8703811, 1)copy SMILEScopy InChI
Affinity DataIC50: 420nMAssay Description:Assay was determined using a continuous assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5MFQPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM92604(DHOD Inhibitor, 3 | US8703811, 1)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Assay was determined using a continuous assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5MFQPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
Harvard Medical School

LigandPNGBDBM92604(DHOD Inhibitor, 3 | US8703811, 1)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WD3Z7PUS Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM92604(DHOD Inhibitor, 3 | US8703811, 1)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WD3Z7PUS Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium vivax)
Harvard Medical School

LigandPNGBDBM92604(DHOD Inhibitor, 3 | US8703811, 1)copy SMILEScopy InChI
Affinity DataIC50: 420nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WD3Z7PUS Patent
TargetDihydroorotate dehydrogenase (fumarate)(Saccharomyces cerevisiae)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM92604(DHOD Inhibitor, 3 | US8703811, 1)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WD3Z7PUS Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM92604(DHOD Inhibitor, 3 | US8703811, 1)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WD3Z7PUS Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
Harvard Medical School

LigandPNGBDBM92604(DHOD Inhibitor, 3 | US8703811, 1)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WD3Z7PUS Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
Harvard Medical School

LigandPNGBDBM92604(DHOD Inhibitor, 3 | US8703811, 1)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WD3Z7PUS Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Harvard Medical School

LigandPNGBDBM92604(DHOD Inhibitor, 3 | US8703811, 1)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WD3Z7PUS Patent