null

SMILES Cc1nc(C(=O)NCCN2CCN(CC2)c2cccc(Cl)c2Cl)c(C)n1-c1ccccc1

InChI Key InChIKey=QDRMTYQLXZSORG-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 9274   

Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Green Cross Corporation

US Patent
LigandPNGBDBM9274(CHEMBL1822893 | US8835436, Example 8)copy SMILEScopy InChI
Affinity DataIC50: 66nMpH: 7.4Assay Description:For serotonin 5-HT2A binding, an aliquot of human recombinant serotonin 5-HT2A receptor (PerkinElmer Life and Analytical Sciences, USA) expressed in ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24T6H2HUS Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Green Cross Corporation

US Patent
LigandPNGBDBM9274(CHEMBL1822893 | US8835436, Example 8)copy SMILEScopy InChI
Affinity DataIC50: 66nMpH: 7.4Assay Description:For serotonin transporter binding assays, a reaction mixture with a final volume of 0.25 ml was prepared by mixing a test compound, human serotonin t...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24T6H2HUS Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Green Cross Corporation

US Patent
LigandPNGBDBM9274(CHEMBL1822893 | US8835436, Example 8)copy SMILEScopy InChI
Affinity DataIC50: 31nMpH: 7.4Assay Description:For serotonin 5-HT2A binding, an aliquot of human recombinant serotonin 5-HT2A receptor (PerkinElmer Life and Analytical Sciences, USA) expressed in ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24T6H2HUS Patent
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Green Cross Corporation

Curated by ChEMBL
LigandPNGBDBM9274(CHEMBL1822893 | US8835436, Example 8)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMAssay Description:Inhibition of 5HT1A receptor by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SX6DMCPubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Green Cross Corporation

Curated by ChEMBL
LigandPNGBDBM9274(CHEMBL1822893 | US8835436, Example 8)copy SMILEScopy InChI
Affinity DataIC50: 1.68E+3nMAssay Description:Inhibition of 5HT6 receptor by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SX6DMCPubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Green Cross Corporation

Curated by ChEMBL
LigandPNGBDBM9274(CHEMBL1822893 | US8835436, Example 8)copy SMILEScopy InChI
Affinity DataIC50: 6.80nMAssay Description:Inhibition of 5HT7 receptor by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SX6DMCPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Green Cross Corporation

US Patent
LigandPNGBDBM9274(CHEMBL1822893 | US8835436, Example 8)copy SMILEScopy InChI
Affinity DataIC50: 129nMAssay Description:Displacement of [3H]impiramine from human serotonin transporter membrane expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SX6DMCPubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Green Cross Corporation

Curated by ChEMBL
LigandPNGBDBM9274(CHEMBL1822893 | US8835436, Example 8)copy SMILEScopy InChI
Affinity DataIC50: 2.19E+3nMAssay Description:Inhibition of dopamine D3 receptor by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SX6DMCPubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Green Cross Corporation

Curated by ChEMBL
LigandPNGBDBM9274(CHEMBL1822893 | US8835436, Example 8)copy SMILEScopy InChI
Affinity DataIC50: 3.94E+3nMAssay Description:inhibition of dopamine D4 receptor by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SX6DMCPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Green Cross Corporation

Curated by ChEMBL
LigandPNGBDBM9274(CHEMBL1822893 | US8835436, Example 8)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]astemizole from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SX6DMCPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Green Cross Corporation

US Patent
LigandPNGBDBM9274(CHEMBL1822893 | US8835436, Example 8)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Displacement of [3H]ketanserin from human recombinant serotonin 5-HT2A receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SX6DMCPubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Green Cross Corporation

US Patent
LigandPNGBDBM9274(CHEMBL1822893 | US8835436, Example 8)copy SMILEScopy InChI
Affinity DataIC50: 66nMAssay Description:Displacement of [3H]mesulergine from human recombinant 5-HT2C receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SX6DMCPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Green Cross Corporation

Curated by ChEMBL
LigandPNGBDBM9274(CHEMBL1822893 | US8835436, Example 8)copy SMILEScopy InChI
Affinity DataIC50: 908nMAssay Description:Inhibition of dopamine D2 receptor by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SX6DMCPubMed