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SMILES C(CCCCNc1ccncc1)CCCCNc1c2CCCCc2nc2ccccc12

InChI Key InChIKey=SOARTDIDZFKTKX-UHFFFAOYSA-N

PDB links: 4 PDB IDs contain inhibitors having a similarity of 90% to this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 9437   

TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM9437(CHEMBL1084530 | Heterodimeric Tacrine-Based Inhibi...)copy SMILEScopy InChI
Affinity DataIC50: 83.6nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W957CHPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM9437(CHEMBL1084530 | Heterodimeric Tacrine-Based Inhibi...)copy SMILEScopy InChI
Affinity DataIC50: 83nMAssay Description:Inhibition of AChEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7GFMPubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM9437(CHEMBL1084530 | Heterodimeric Tacrine-Based Inhibi...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W957CHPubMed