null

SMILES O=c1cc(Cn2ccnc2)c2ccc(OCc3ccccc3)cc2o1

InChI Key InChIKey=IWVOYZQRBNJWPZ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 9485   

TargetAromatase(Homo sapiens (Human))
University of Bari

LigandPNGBDBM9485(7-(benzyloxy)-4-(1H-imidazol-1-ylmethyl)-2H-chrome...)copy SMILEScopy InChI
Affinity DataIC50: 150nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3R0CPubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of Bari

LigandPNGBDBM9485(7-(benzyloxy)-4-(1H-imidazol-1-ylmethyl)-2H-chrome...)copy SMILEScopy InChI
Affinity DataAssay Description:The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3R0CPubMed
TargetAromatase(Homo sapiens (Human))
University of Bari

LigandPNGBDBM9485(7-(benzyloxy)-4-(1H-imidazol-1-ylmethyl)-2H-chrome...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of human placental microsomal CYP19 using [1beta-3H]androstenedione substrate pre-incubated for 5 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56MC3PubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Universit£ degli Studi di Bari"Aldo Moro"

Curated by ChEMBL
LigandPNGBDBM9485(7-(benzyloxy)-4-(1H-imidazol-1-ylmethyl)-2H-chrome...)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZh11B1 cells using [1,2-3H]-11-deoxycorticosterone substrate incubated for 25 mins by HPLC metho...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56MC3PubMed
TargetAromatase(Homo sapiens (Human))
University of Bari

LigandPNGBDBM9485(7-(benzyloxy)-4-(1H-imidazol-1-ylmethyl)-2H-chrome...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of human placental microsome CYP19 using [1beta-3H] androstenedione as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X583QPubMed
TargetAromatase(Homo sapiens (Human))
University of Bari

LigandPNGBDBM9485(7-(benzyloxy)-4-(1H-imidazol-1-ylmethyl)-2H-chrome...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of human aromatase-mediated conversion of [1beta3H]androstenedione to estrone by liquid scintillation counting in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9080PubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Universit£ degli Studi di Bari"Aldo Moro"

Curated by ChEMBL
LigandPNGBDBM9485(7-(benzyloxy)-4-(1H-imidazol-1-ylmethyl)-2H-chrome...)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Inhibition of human CYP11B1 expressed in Chinese hamster V79MZ cells using [1,2-3H]11-deoxycorticosterone/11-deoxycorticosteroneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X583QPubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Universita` degli Studi di Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM9485(7-(benzyloxy)-4-(1H-imidazol-1-ylmethyl)-2H-chrome...)copy SMILEScopy InChI
Affinity DataIC50: 289nMAssay Description:Inhibition of human CYP11B2 expressed in Chinese hamster V79MZ cells using [1,2-3H]11-deoxycorticosterone/11-deoxycorticosteroneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X583QPubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Universita` degli Studi di Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM9485(7-(benzyloxy)-4-(1H-imidazol-1-ylmethyl)-2H-chrome...)copy SMILEScopy InChI
Affinity DataIC50: 289nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZh11B2 cells using [1,2-3H]-11-deoxycorticosterone substrate incubated for 25 mins by HPLC metho...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56MC3PubMed