null
SMILES O=c1cc(Cn2ccnc2)c2ccc(OCc3ccccc3)cc2o1
InChI Key InChIKey=IWVOYZQRBNJWPZ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 9485
Affinity DataIC50: 150nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...More data for this Ligand-Target Pair
Affinity DataAssay Description:The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of human placental microsomal CYP19 using [1beta-3H]androstenedione substrate pre-incubated for 5 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Universit£ degli Studi di Bari"Aldo Moro"
Curated by ChEMBL
Universit£ degli Studi di Bari"Aldo Moro"
Curated by ChEMBL
Affinity DataIC50: 72nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZh11B1 cells using [1,2-3H]-11-deoxycorticosterone substrate incubated for 25 mins by HPLC metho...More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of human placental microsome CYP19 using [1beta-3H] androstenedione as a substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of human aromatase-mediated conversion of [1beta3H]androstenedione to estrone by liquid scintillation counting in presence of NADPHMore data for this Ligand-Target Pair
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Universit£ degli Studi di Bari"Aldo Moro"
Curated by ChEMBL
Universit£ degli Studi di Bari"Aldo Moro"
Curated by ChEMBL
Affinity DataIC50: 72nMAssay Description:Inhibition of human CYP11B1 expressed in Chinese hamster V79MZ cells using [1,2-3H]11-deoxycorticosterone/11-deoxycorticosteroneMore data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Universita` degli Studi di Bari Aldo Moro
Curated by ChEMBL
Universita` degli Studi di Bari Aldo Moro
Curated by ChEMBL
Affinity DataIC50: 289nMAssay Description:Inhibition of human CYP11B2 expressed in Chinese hamster V79MZ cells using [1,2-3H]11-deoxycorticosterone/11-deoxycorticosteroneMore data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Universita` degli Studi di Bari Aldo Moro
Curated by ChEMBL
Universita` degli Studi di Bari Aldo Moro
Curated by ChEMBL
Affinity DataIC50: 289nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZh11B2 cells using [1,2-3H]-11-deoxycorticosterone substrate incubated for 25 mins by HPLC metho...More data for this Ligand-Target Pair