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SMILES Brc1ccc(cc1)[C@@H](c1coc2ccccc2c1=O)n1ccnc1

InChI Key InChIKey=CRDMIHRISHLNPC-SFHVURJKSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 9917   

TargetAromatase(Homo sapiens (Human))
University of Bologna

LigandPNGBDBM9917(3-[(S)-(4-bromophenyl)(1H-imidazol-1-yl)methyl]-4H...)copy SMILEScopy InChI
Affinity DataIC50: 290nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9NN9PubMed
TargetAromatase(Homo sapiens (Human))
University of Bologna

LigandPNGBDBM9917(3-[(S)-(4-bromophenyl)(1H-imidazol-1-yl)methyl]-4H...)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:Inhibition of human aromatase-mediated conversion of [1beta3H]androstenedione to estrone by liquid scintillation counting in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9080PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of Bologna

LigandPNGBDBM9917(3-[(S)-(4-bromophenyl)(1H-imidazol-1-yl)methyl]-4H...)copy SMILEScopy InChI
Affinity DatapH: 7.4 T: 2°CAssay Description:The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9NN9PubMed