null

SMILES Cc1ccc(Nc2ccc(cc2S(=O)(=O)NC(=O)NC(C)(C)C)[N+]([O-])=O)cc1

InChI Key InChIKey=SILRUCMXYIKULW-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50188619   

TargetThromboxane A2 receptor(Homo sapiens (Human))
University of Li&eagrove;ge

Curated by PDSP Ki Database
LigandPNGBDBM50188619(1-(2-(p-toluidino)-5-nitrophenylsulfonyl)-3-tert-b...)copy SMILEScopy InChI
Affinity DataKi:  0.800nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9GVJPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
University of Li&eagrove;ge

Curated by PDSP Ki Database
LigandPNGBDBM50188619(1-(2-(p-toluidino)-5-nitrophenylsulfonyl)-3-tert-b...)copy SMILEScopy InChI
Affinity DataKi:  1.10nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9GVJPubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
University of Li&eagrove;ge

Curated by PDSP Ki Database
LigandPNGBDBM50188619(1-(2-(p-toluidino)-5-nitrophenylsulfonyl)-3-tert-b...)copy SMILEScopy InChI
Affinity DataKi:  1.30nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9GVJPubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
University of Li&eagrove;ge

Curated by PDSP Ki Database
LigandPNGBDBM50188619(1-(2-(p-toluidino)-5-nitrophenylsulfonyl)-3-tert-b...)copy SMILEScopy InChI
Affinity DataIC50: 1.05nMAssay Description:Displacement of [3H]SQ29,548 from TPalpha receptor (short isoform) expressed in COS7 cells at 1 uMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63MJTPubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
University of Li&eagrove;ge

Curated by PDSP Ki Database
LigandPNGBDBM50188619(1-(2-(p-toluidino)-5-nitrophenylsulfonyl)-3-tert-b...)copy SMILEScopy InChI
Affinity DataIC50: 0.780nMAssay Description:Displacement of [3H]SQ29,548 from TPbeta receptor (long isoform) expressed in COS7 cells at 1 uMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63MJTPubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
University of Li&eagrove;ge

Curated by PDSP Ki Database
LigandPNGBDBM50188619(1-(2-(p-toluidino)-5-nitrophenylsulfonyl)-3-tert-b...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of U46619-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63MJTPubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
University of Li&eagrove;ge

Curated by PDSP Ki Database
LigandPNGBDBM50188619(1-(2-(p-toluidino)-5-nitrophenylsulfonyl)-3-tert-b...)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Antagonist activity at human thromboxane A2 receptor isoform beta expressed in HEK293 cells assessed as inhibition of U46619-induced calcium mobiliza...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB7497PubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
University of Li&eagrove;ge

Curated by PDSP Ki Database
LigandPNGBDBM50188619(1-(2-(p-toluidino)-5-nitrophenylsulfonyl)-3-tert-b...)copy SMILEScopy InChI
Affinity DataIC50: 620nMAssay Description:Antagonist activity at human thromboxane A2 receptor beta over-expressed in HEK293 cells assessed as inhibition of U-46619-induced intracellular calc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95BMWPubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
University of Li&eagrove;ge

Curated by PDSP Ki Database
LigandPNGBDBM50188619(1-(2-(p-toluidino)-5-nitrophenylsulfonyl)-3-tert-b...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Antagonist activity at human thromboxane A2 receptor alpha over-expressed in HEK293 cells assessed as inhibition of U-46619-induced intracellular cal...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95BMWPubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
University of Li&eagrove;ge

Curated by PDSP Ki Database
LigandPNGBDBM50188619(1-(2-(p-toluidino)-5-nitrophenylsulfonyl)-3-tert-b...)copy SMILEScopy InChI
Affinity DataIC50: 53.1nMAssay Description:Activity at TPbeta (long isoform) receptor expressed in HEK293 cells assessed as ability to antagonize U46619-mediated calcium ion mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63MJTPubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
University of Li&eagrove;ge

Curated by PDSP Ki Database
LigandPNGBDBM50188619(1-(2-(p-toluidino)-5-nitrophenylsulfonyl)-3-tert-b...)copy SMILEScopy InChI
Affinity DataIC50: 319nMAssay Description:Antagonist activity at human thromboxane A2 receptor isoform alpha expressed in HEK293 cells assessed as inhibition of U46619-induced calcium mobiliz...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB7497PubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
University of Li&eagrove;ge

Curated by PDSP Ki Database
LigandPNGBDBM50188619(1-(2-(p-toluidino)-5-nitrophenylsulfonyl)-3-tert-b...)copy SMILEScopy InChI
Affinity DataIC50: 319nMAssay Description:Activity at TPalpha (short isoform) receptor expressed in HEK293 cells assessed as ability to antagonize U46619-mediated calcium ion mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63MJTPubMed