null

SMILES COc1cc(cc(OC)c1OC)C(=O)C(=O)N1CCCC[C@H]1C(=O)OC(CCCc1cccnc1)CCCc1cccnc1

InChI Key InChIKey=CGVWPQOFHSAKRR-NDEPHWFRSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50109811   

TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109811((S)-1-[2-Oxo-2-(3,4,5-trimethoxy-phenyl)-acetyl]-p...)copy SMILEScopy InChI
Affinity DataIC50: 5.18E+3nMAssay Description:Inhibition of multidrug resistance associated protein type 1 (MRP1) assayed by an accumulation assay in COR.L23/R cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetATP-dependent translocase ABCB1(Mus musculus)
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109811((S)-1-[2-Oxo-2-(3,4,5-trimethoxy-phenyl)-acetyl]-p...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity against P-glyco-protein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP4(Homo sapiens (Human))
Max Planck Institute of Psychiatry

Curated by ChEMBL
LigandPNGBDBM50109811((S)-1-[2-Oxo-2-(3,4,5-trimethoxy-phenyl)-acetyl]-p...)copy SMILEScopy InChI
Affinity DataIC50: 7.37E+3nMAssay Description:Binding affinity to FKBP52 FK1 domain by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6SMPPubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP5(Homo sapiens (Human))
Max Planck Institute of Psychiatry

Curated by ChEMBL
LigandPNGBDBM50109811((S)-1-[2-Oxo-2-(3,4,5-trimethoxy-phenyl)-acetyl]-p...)copy SMILEScopy InChI
Affinity DataIC50: 8.52E+3nMAssay Description:Binding affinity to FKBP51 FK1 domain by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6SMPPubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Max Planck Institute of Psychiatry

Curated by ChEMBL
LigandPNGBDBM50109811((S)-1-[2-Oxo-2-(3,4,5-trimethoxy-phenyl)-acetyl]-p...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Binding affinity to FKBP12 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6SMPPubMed