null

SMILES NCc1ccc(cc1)C(=O)N1CCC2(CC1)Nc1cccc(F)c1C(N)=N2

InChI Key InChIKey=SFPCNWQWKOUNRT-UHFFFAOYSA-N

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 36397   

TargetNitric oxide synthase, inducible(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM36397((4-Amino-5-fluorospiro[1H-quinazoline-2,4'-pip...)copy SMILEScopy InChI
Affinity DataIC50: 130nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM36397((4-Amino-5-fluorospiro[1H-quinazoline-2,4'-pip...)copy SMILEScopy InChI
Affinity DataIC50: 7.80E+3nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB443QPubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM36397((4-Amino-5-fluorospiro[1H-quinazoline-2,4'-pip...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB443QPubMed