null
SMILES COc1ccc2c(c[n+](C)c3c4cc5OCOc5cc4ccc23)c1OC
InChI Key InChIKey=LLEJIEBFSOEYIV-UHFFFAOYSA-N
PDB links: 6 PDB IDs match this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 26 hits for monomerid = 25524
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Sunchon National University
Curated by ChEMBL
Sunchon National University
Curated by ChEMBL
Affinity DataKi: 220nMAssay Description:Competitive inhibition of recombinant human MAO-A using kynuramine as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 320nMAssay Description:Competitive inhibition of human AChE using acetyl thiocholine iodide as substrate by Lineweaver-Burk double-reciprocal analysisMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Abo Akademi University
Curated by ChEMBL
Abo Akademi University
Curated by ChEMBL
Affinity DataKi: 480nMAssay Description:Competitive inhibition of electric eel AChE using acetyl thiocholine iodide as substrate by Lineweaver-Burk double-reciprocal analysisMore data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Rattus norvegicus (Rat))
Temple University
Curated by PDSP Ki Database
Temple University
Curated by PDSP Ki Database
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Abo Akademi University
Curated by ChEMBL
Abo Akademi University
Curated by ChEMBL
Affinity DataKi: 920nMAssay Description:Uncompetitive inhibition of electric eel AChE using acetyl thiocholine iodide as substrate by Lineweaver-Burk double-reciprocal analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.12E+3nMAssay Description:Uncompetitive inhibition of human AChE using acetyl thiocholine iodide as substrate by Lineweaver-Burk double-reciprocal analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.06E+5nMAssay Description:Displacement of Flu-Bak peptide from recombinant antiapoptopic Bcl-w protein by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.71E+5nMAssay Description:Displacement of Flu-Bak peptide from recombinant antiapoptopic Bcl2 protein by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of PKCepsilonChecked by AuthorMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Sunchon National University
Curated by ChEMBL
Sunchon National University
Curated by ChEMBL
Affinity DataIC50: 550nMAssay Description:Inhibition of recombinant human MAO-A using kynuramine as substrate incubated for 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Sunchon National University
Curated by ChEMBL
Sunchon National University
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant human MAO-B using benzylamine as substrate incubated for 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 5.74E+5nMAssay Description:Inhibition of HIV1 RTMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Vitae Pharmaceuticals, Inc.
Curated by ChEMBL
Vitae Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataIC50: 566nMAssay Description:Binding affinity to human 6xHis-tagged PPARgamma ligand binding domain (206 to 477 residues) by TR-FRET assayMore data for this Ligand-Target Pair
3D Structure (crystal)TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Homo sapiens (Human))
University of Chemistry and Technology Prague
Curated by ChEMBL
University of Chemistry and Technology Prague
Curated by ChEMBL
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of SERCA1a (unknown origin) incubated for 10 mins by enzyme-coupled methodMore data for this Ligand-Target Pair
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
University of Chemistry and Technology Prague
Curated by ChEMBL
University of Chemistry and Technology Prague
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of rabbit skeletal muscle microsomes SERCA1a incubated for 10 mins by enzyme-coupled methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibition of AChE (unknown origin) preincubated for 30 mins followed by substrate addition acetylthiocholineiodide measured after 40 mins by Ellman'...More data for this Ligand-Target Pair
Affinity DataIC50: 8.58E+3nMAssay Description:Inhibition of BuChE (unknown origin) preincubated for 30 mins followed by substrate addition acetylthiocholineiodide measured after 40 mins by Ellman...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Vitae Pharmaceuticals, Inc.
Curated by ChEMBL
Vitae Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of human BChE by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Abo Akademi University
Curated by ChEMBL
Abo Akademi University
Curated by ChEMBL
Affinity DataIC50: 3.78E+3nMAssay Description:Inhibition of electric eel AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of human AChE by Ellman's methodMore data for this Ligand-Target Pair
TargetRas-related C3 botulinum toxin substrate 1(Homo sapiens (Human))
Exonhit Therapeutics
Curated by ChEMBL
Exonhit Therapeutics
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Rac1 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assayMore data for this Ligand-Target Pair
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Exonhit Therapeutics
Curated by ChEMBL
Exonhit Therapeutics
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Cdc42 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assayMore data for this Ligand-Target Pair
TargetAromatic-L-amino-acid decarboxylase(Homo sapiens (Human))
Hunan Agricultural University
Curated by ChEMBL
Hunan Agricultural University
Curated by ChEMBL
Affinity DataIC50: 1.28E+6nMAssay Description:Inhibition of recombinant human DOPA decarboxylase assessed as inhibition of dopamine production after 30 mins by HPLC methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex...More data for this Ligand-Target Pair
Affinity DataIC50: 6.33E+3nMAssay Description:Inhibition of horse BChE by Ellman's methodMore data for this Ligand-Target Pair