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SMILES N[C@H](CO)C(O)=O

InChI Key InChIKey=MTCFGRXMJLQNBG-UWTATZPHSA-N

PDB links: 159 PDB IDs match this monomer. 76 PDB IDs contain this monomer as substructures. 76 PDB IDs contain inhibitors having a similarity of 90% to this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 23167   

TargetProton-coupled amino acid transporter 1(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM23167((2R)-2-amino-3-hydroxypropanoic acid | CHEMBL28512...)copy SMILEScopy InChI
Affinity DataKi:  2.20E+7nMAssay Description:Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation countingChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ882DPubMed
LigandPNGBDBM23167((2R)-2-amino-3-hydroxypropanoic acid | CHEMBL28512...)copy SMILEScopy InChI
Affinity DataEC50:  150nMAssay Description:Agonist activity at rat GluN1/GluN2D NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))TBA
LigandPNGBDBM23167((2R)-2-amino-3-hydroxypropanoic acid | CHEMBL28512...)copy SMILEScopy InChI
Affinity DataEC50:  620nMAssay Description:Agonist activity at rat GluN1/GluN2B NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...More data for this Ligand-Target Pair
LigandPNGBDBM23167((2R)-2-amino-3-hydroxypropanoic acid | CHEMBL28512...)copy SMILEScopy InChI
Affinity DataEC50:  190nMAssay Description:Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Institut de Recherches Servier

Curated by ChEMBL
LigandPNGBDBM23167((2R)-2-amino-3-hydroxypropanoic acid | CHEMBL28512...)copy SMILEScopy InChI
Affinity DataIC50: 670nMAssay Description:In vitro inhibitory activity of the compound to inhibit [3H]-glycine binding to NMDA receptorMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rattus norvegicus (Rat))TBA
LigandPNGBDBM23167((2R)-2-amino-3-hydroxypropanoic acid | CHEMBL28512...)copy SMILEScopy InChI
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at rat GluN1/GluN2A NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...More data for this Ligand-Target Pair