null

SMILES COc1cc(CC(C)N)c(OC)cc1C

InChI Key InChIKey=NTJQREUGJKIARY-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 22 hits for monomerid = 50005265   

Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Stanford University

Curated by PDSP Ki Database
LigandPNGBDBM50005265((+/-)2-(2,5-Dimethoxy-4-methyl-phenyl)-1-methyl-et...)copy SMILEScopy InChI
Affinity DataKi:  4.80nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FX77Z2PubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50005265((+/-)2-(2,5-Dimethoxy-4-methyl-phenyl)-1-methyl-et...)copy SMILEScopy InChI
Affinity DataKi:  8nMAssay Description:Effect on plasma amine oxidase (0.1 uM) after 15 min of incubation at pH 7.2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65SBPubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50005265((+/-)2-(2,5-Dimethoxy-4-methyl-phenyl)-1-methyl-et...)copy SMILEScopy InChI
Affinity DataKi:  19nMAssay Description:Binding affinity against 5-hydroxytryptamine 2 receptor from rat frontal cortex using [125]-(R)-DOI as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC3535PubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Stanford University

Curated by PDSP Ki Database
LigandPNGBDBM50005265((+/-)2-(2,5-Dimethoxy-4-methyl-phenyl)-1-methyl-et...)copy SMILEScopy InChI
Affinity DataKi:  19nMAssay Description:Compound was evaluated for its ability to displace [125I]-(R)-DOI from 5-hydroxytryptamine 2A receptor in cloned rat prefrontal cortex homogenateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8RH5PubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50005265((+/-)2-(2,5-Dimethoxy-4-methyl-phenyl)-1-methyl-et...)copy SMILEScopy InChI
Affinity DataKi:  19nMAssay Description:Compound was evaluated for its ability to displace 0.25 nM [125I](R)-DOI from binding sites in rat frontal cortex.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN0C6JPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Albany Medical College

Curated by PDSP Ki Database
LigandPNGBDBM50005265((+/-)2-(2,5-Dimethoxy-4-methyl-phenyl)-1-methyl-et...)copy SMILEScopy InChI
Affinity DataKi:  21nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7NDXPubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
University of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM50005265((+/-)2-(2,5-Dimethoxy-4-methyl-phenyl)-1-methyl-et...)copy SMILEScopy InChI
Affinity DataKi:  41.7nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M043X2PubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50005265((+/-)2-(2,5-Dimethoxy-4-methyl-phenyl)-1-methyl-et...)copy SMILEScopy InChI
Affinity DataKi:  100nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor from frontal cortical regions of male Sprague-Dawley rat homogenates, using [3H]ketanserin as...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4BV4PubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50005265((+/-)2-(2,5-Dimethoxy-4-methyl-phenyl)-1-methyl-et...)copy SMILEScopy InChI
Affinity DataKi:  100nMAssay Description:Binding affinity against 5-hydroxytryptamine 2 receptor of rat frontal cortex using [3H]ketanserin radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319Z37PubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50005265((+/-)2-(2,5-Dimethoxy-4-methyl-phenyl)-1-methyl-et...)copy SMILEScopy InChI
Affinity DataKi:  100nMAssay Description:Binding affinity to rat cortical membranes at 5-hydroxytryptamine 2 (5-HT2) receptor using [3H]KET as a radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4BS7PubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Stanford University

Curated by PDSP Ki Database
LigandPNGBDBM50005265((+/-)2-(2,5-Dimethoxy-4-methyl-phenyl)-1-methyl-et...)copy SMILEScopy InChI
Affinity DataKi:  100nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor in Sprague-Dawley rat brain by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8RNZPubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50005265((+/-)2-(2,5-Dimethoxy-4-methyl-phenyl)-1-methyl-et...)copy SMILEScopy InChI
Affinity DataKi:  100nMAssay Description:Effect on plasma amine oxidase (0.1 uM) after 30 min of incubation at pH 7.2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65SBPubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
University of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM50005265((+/-)2-(2,5-Dimethoxy-4-methyl-phenyl)-1-methyl-et...)copy SMILEScopy InChI
Affinity DataKi:  193nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1C receptor from frontal cortical regions of male Sprague-Dawley rat homogenates, using [3H]mesulergine ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4BV4PubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Albany Medical College

Curated by PDSP Ki Database
LigandPNGBDBM50005265((+/-)2-(2,5-Dimethoxy-4-methyl-phenyl)-1-methyl-et...)copy SMILEScopy InChI
Affinity DataKi:  306nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7NDXPubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
University of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM50005265((+/-)2-(2,5-Dimethoxy-4-methyl-phenyl)-1-methyl-et...)copy SMILEScopy InChI
Affinity DataKi:  372nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M043X2PubMed
Target5-hydroxytryptamine receptor 2B(BOVINE)
Stanford University

Curated by PDSP Ki Database
LigandPNGBDBM50005265((+/-)2-(2,5-Dimethoxy-4-methyl-phenyl)-1-methyl-et...)copy SMILEScopy InChI
Affinity DataKi:  400nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FX77Z2PubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50005265((+/-)2-(2,5-Dimethoxy-4-methyl-phenyl)-1-methyl-et...)copy SMILEScopy InChI
Affinity DataKi:  2.07E+3nMAssay Description:Binding affinity against 5-HT1B serotonin receptor in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65SBPubMed
LigandPNGBDBM50005265((+/-)2-(2,5-Dimethoxy-4-methyl-phenyl)-1-methyl-et...)copy SMILEScopy InChI
Affinity DataKi:  2.89E+3nMAssay Description:Evaluated for binding affinity towards rat cortical membranes at 5-hydroxytryptamine 1 receptor binding site by using [3H]-5-HT as a radioligand.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4BS7PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50005265((+/-)2-(2,5-Dimethoxy-4-methyl-phenyl)-1-methyl-et...)copy SMILEScopy InChI
Affinity DataKi:  5.13E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A receptor in rat hippocampal tissueMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65SBPubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50005265((+/-)2-(2,5-Dimethoxy-4-methyl-phenyl)-1-methyl-et...)copy SMILEScopy InChI
Affinity DataKi:  7.27E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ64JGPubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Universidad de Chile

Curated by ChEMBL
LigandPNGBDBM50005265((+/-)2-(2,5-Dimethoxy-4-methyl-phenyl)-1-methyl-et...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibitory concentration against monoamine oxidase A in rat brain mitochondrial suspensionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27080XXPubMed
Target5-hydroxytryptamine receptor 2B(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50005265((+/-)2-(2,5-Dimethoxy-4-methyl-phenyl)-1-methyl-et...)copy SMILEScopy InChI
Affinity DataKd:  75.9nMAssay Description:Affinity against 5-hydroxytryptamine 2B receptor in the isolated rat stomach fundusMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6FD3PubMed