null

SMILES OC1=NC(=O)C(N1)(c1ccccc1)c1ccccc1

InChI Key InChIKey=CXOFVDLJLONNDW-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50101816   

TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50101816(CHEBI:8107 | Dilabid | Dilantin | Dilantin-125 | D...)copy SMILEScopy InChI
Affinity DataKi:  5.34E+4nMAssay Description:Binding affinity to Nav 1.2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P12XT
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50101816(CHEBI:8107 | Dilabid | Dilantin | Dilantin-125 | D...)copy SMILEScopy InChI
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of L-type calcium channel measured using 2-electrode voltage-clamp in human embryonic kidney cells heterologically expressing alpha-1C sub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79D5CPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
University of Alabama

Curated by ChEMBL
LigandPNGBDBM50101816(CHEBI:8107 | Dilabid | Dilantin | Dilantin-125 | D...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:In vitro inhibition of [3H]-BTX-B binding to sodium channels in rat brain synapto-neurosomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC927CPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
University of Alabama

Curated by ChEMBL
LigandPNGBDBM50101816(CHEBI:8107 | Dilabid | Dilantin | Dilantin-125 | D...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of [3H]BTX-B binding to Neuronal voltage-dependent sodium channel of rat cerebral cortex synaptoneurosomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J96931PubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
University of Alabama

Curated by ChEMBL
LigandPNGBDBM50101816(CHEBI:8107 | Dilabid | Dilantin | Dilantin-125 | D...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:In vitro inhibition of Voltage-gated sodium channel by the displacement of [3H]batrachotoxin A 20-alpha-benzoate in rat brain cerebral cortex synapto...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4N61PubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
University of Alabama

Curated by ChEMBL
LigandPNGBDBM50101816(CHEBI:8107 | Dilabid | Dilantin | Dilantin-125 | D...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of [3H]BTX-B binding to neurotoxin site 2 of sodium channel of rat cerebral cortex synaptoneurosomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1NM8PubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
University of Alabama

Curated by ChEMBL
LigandPNGBDBM50101816(CHEBI:8107 | Dilabid | Dilantin | Dilantin-125 | D...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of binding to sodium channel of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4TB8PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Cavia porcellus)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50101816(CHEBI:8107 | Dilabid | Dilantin | Dilantin-125 | D...)copy SMILEScopy InChI
Affinity DataIC50: 1.03E+5nMAssay Description:Inhibition of L-type calcium channel measured using whole-cell patch clamp in rat ventricular myocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79D5CPubMed
LigandPNGBDBM50101816(CHEBI:8107 | Dilabid | Dilantin | Dilantin-125 | D...)copy SMILEScopy InChI
Affinity DataIC50: 2.19E+4nMAssay Description:Inhibition of Cav1.2 current measured using QPatch automatic path clamp system in CHO cells expressing Cav1.2, beta-2 and alpha-2/delta-1 subunitsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB77K2PubMed