null
SMILES CN1CCc2cc(Cl)c(O)cc2[C@@H]2[C@@H]1CCc1ccccc21
InChI Key InChIKey=DMJWENQHWZZWDF-PKOBYXMFSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 21 hits for monomerid = 50004823
Affinity DataKi: 0.900nMAssay Description:Binding affinity to human dopamine D1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]SCh23390 from dopamine D1 receptor expressed in mouse LTK cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Binding affinity to dopamine D1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Inhibition of [3H]-SCH-23,390 binding to rat striatal homogenate dopamine receptor D1More data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Binding affinity to displace [3H]-SCH- 23390 against Dopamine receptor D1More data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Compound was tested for the displacement of [3H]-SCH- 23390 from dopamine receptor D1More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of radioligand from dopamine D5 receptor expressed in mouse LTK cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Binding affinity to dopamine D5 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Schering-Plough Corporation
Curated by PDSP Ki Database
Schering-Plough Corporation
Curated by PDSP Ki Database
Affinity DataKi: 514nMAssay Description:Displacement of [3H]-spiperone from rat striatal homogenate dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataKi: 980nMAssay Description:Binding affinity to dopamine D2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 980nMAssay Description:Displacement of [3H]methylspiperon from dopamine D2 receptor expressed in mouse LTK cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.24E+3nMAssay Description:Binding affinity to human dopamine D2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 5.52E+3nMAssay Description:Binding affinity to dopamine D4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 5.52E+3nMAssay Description:Displacement of radioligand from dopamine D4 receptor expressed in mouse LTK cells by scintillation countingMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
National Institutes of Health Chemical Genomics Center
Curated by ChEMBL
National Institutes of Health Chemical Genomics Center
Curated by ChEMBL
Affinity DataEC50: 1.26E+4nMAssay Description:Activation of human PXR expressed in human HepG2 (DPX-2) cells assessed as induction of CYP3A4 after 24 hrs by luminescent analysisMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
National Institutes of Health Chemical Genomics Center
Curated by ChEMBL
National Institutes of Health Chemical Genomics Center
Curated by ChEMBL
Affinity DataEC50: 4.00E+3nMAssay Description:Activation of human PXR expressed in human HepG2 (DPX-2) cells after 24 hrs by luciferase reporter gene based luminescent analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Antagonist activity at human dopamine D1 receptor expressed in CHO-K1 cells by cAMP Hunter assayMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
National Institutes of Health Chemical Genomics Center
Curated by ChEMBL
National Institutes of Health Chemical Genomics Center
Curated by ChEMBL
Affinity DataEC50: 6.30E+3nMAssay Description:Competitive binding affinity to human PXR LBD (111 to 434) by TR-FRET assayMore data for this Ligand-Target Pair