null

SMILES Clc1ccc(cc1)N1CCN(Cc2cnn3ccccc23)CC1

InChI Key InChIKey=XVPRVMIFXXOEFR-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 43 hits for monomerid = 50073805   

TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£t Erlangen-N£rnberg

Curated by ChEMBL
LigandPNGBDBM50073805(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Binding affinity evaluated for the displacement of [3H]spiperone against human dopamine receptor D4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20Z73SGPubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£t Erlangen-N£rnberg

Curated by ChEMBL
LigandPNGBDBM50073805(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)copy SMILEScopy InChI
Affinity DataKi:  2.29nMAssay Description:Ability to displace [3H]spiperone from dopamine receptor D4.4 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959M91PubMed
TargetD(4) dopamine receptor(RAT)
Forschungszentrum J£lich GmbH

Curated by ChEMBL
LigandPNGBDBM50073805(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)copy SMILEScopy InChI
Affinity DataKi:  2.60nMAssay Description:Binding affinity to dopamine D4 receptor in Wistar rat brain slicesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W096B2PubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£t Erlangen-N£rnberg

Curated by ChEMBL
LigandPNGBDBM50073805(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)copy SMILEScopy InChI
Affinity DataKi:  3.10nMAssay Description:Ability to displace [3H]SCH-23390 radioligand from cloned human Dopamine receptor D2 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72J0VPubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£t Erlangen-N£rnberg

Curated by ChEMBL
LigandPNGBDBM50073805(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)copy SMILEScopy InChI
Affinity DataKi:  3.10nMAssay Description:In vitro binding affinity at human cloned dopamine receptor D2 (short) stably expressed in CHO cells by [3H]spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM2B5XPubMed
TargetD(4) dopamine receptor(RAT)
Forschungszentrum J£lich GmbH

Curated by ChEMBL
LigandPNGBDBM50073805(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)copy SMILEScopy InChI
Affinity DataKi:  3.10nMAssay Description:Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by PDSP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25140RWPubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£t Erlangen-N£rnberg

Curated by ChEMBL
LigandPNGBDBM50073805(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)copy SMILEScopy InChI
Affinity DataKi:  3.10nMMore data for this Ligand-Target Pair
In DepthDetails
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£t Erlangen-N£rnberg

Curated by ChEMBL
LigandPNGBDBM50073805(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)copy SMILEScopy InChI
Affinity DataKi:  3.60nMAssay Description:Biniding affinity for Dopamine receptor D4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H131HWPubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£t Erlangen-N£rnberg

Curated by ChEMBL
LigandPNGBDBM50073805(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)copy SMILEScopy InChI
Affinity DataKi:  3.60nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D4.4 in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KZ5PubMed
Target5-hydroxytryptamine receptor 2A(PIG)
Laboratoire de Chimie Th�rapeutique

Curated by ChEMBL
LigandPNGBDBM50073805(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)copy SMILEScopy InChI
Affinity DataKi:  380nMAssay Description:Displacement of [3H]ketanserin from 5HT2 receptor in porcine cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KZ5PubMed
Target5-hydroxytryptamine receptor 2A(PIG)
Laboratoire de Chimie Th�rapeutique

Curated by ChEMBL
LigandPNGBDBM50073805(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)copy SMILEScopy InChI
Affinity DataKi:  380nMAssay Description:Displacement of [3H]ketanserin from 5HT2 receptor in pig cortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB75FFPubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Laboratoire de Chimie Th�rapeutique

Curated by ChEMBL
LigandPNGBDBM50073805(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)copy SMILEScopy InChI
Affinity DataKi:  1.40E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in porcine cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KZ5PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50073805(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)copy SMILEScopy InChI
Affinity DataKi:  2.20E+3nMAssay Description:Displacement of [3H]spiperone from cloned human dopamine D2S receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB75FFPubMed
TargetD(1A) dopamine receptor(Sus scrofa)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50073805(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)copy SMILEScopy InChI
Affinity DataKi:  2.80E+3nMAssay Description:Displacement of [3H]SCH23990 from dopamine D1 receptor in pig striatal membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB75FFPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50073805(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)copy SMILEScopy InChI
Affinity DataKi:  2.90E+3nMAssay Description:Displacement of [3H]spiperone from cloned human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB75FFPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50073805(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)copy SMILEScopy InChI
Affinity DataKi:  3.20E+3nMAssay Description:In vitro binding affinity at human cloned dopamine receptor D2 (long) stably expressed in CHO cells by [3H]-Spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM2B5XPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50073805(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)copy SMILEScopy InChI
Affinity DataKi:  3.20E+3nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D2(long) in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KZ5PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50073805(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)copy SMILEScopy InChI
Affinity DataKi:  3.20E+3nMAssay Description:Binding affinity for human dopamine receptor D2 longMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H131HWPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50073805(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)copy SMILEScopy InChI
Affinity DataKi:  3.20E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D2 receptor by PDSP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25140RWPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50073805(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)copy SMILEScopy InChI
Affinity DataKi:  3.20E+3nMMore data for this Ligand-Target Pair
In DepthDetails
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50073805(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)copy SMILEScopy InChI
Affinity DataKi:  3.20E+3nMAssay Description:Inhibition of human dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84FBZPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50073805(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)copy SMILEScopy InChI
Affinity DataKi:  4.30E+3nMAssay Description:In vitro binding affinity at human cloned dopamine receptor D2 (short) stably expressed in CHO cells by [3H]spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM2B5XPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50073805(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)copy SMILEScopy InChI
Affinity DataKi:  4.30E+3nMAssay Description:Ability to displace [3H]SCH-23390 radioligand from cloned human Dopamine receptor D2 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72J0VPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50073805(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)copy SMILEScopy InChI
Affinity DataKi:  4.30E+3nMAssay Description:Ability to displace [3H]spiperone radioligand from cloned human Dopamine receptor D2 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72J0VPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50073805(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)copy SMILEScopy InChI
Affinity DataKi:  4.30E+3nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D2(short) in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KZ5PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50073805(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)copy SMILEScopy InChI
Affinity DataKi:  4.30E+3nMAssay Description:Inhibition of human dopamine D2 (short) receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84FBZPubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50073805(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)copy SMILEScopy InChI
Affinity DataKi:  4.50E+3nMAssay Description:Displacement of [3H]spiperone from cloned human dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB75FFPubMed
TargetD(2) dopamine receptor(BOVINE)
Universit£t Erlangen-N£rnberg

Curated by ChEMBL
LigandPNGBDBM50073805(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)copy SMILEScopy InChI
Affinity DataKi:  4.70E+3nMAssay Description:Binding affinity was evaluated for the displacement of [3H]spiperone against bovine Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20Z73SGPubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50073805(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)copy SMILEScopy InChI
Affinity DataKi:  5.00E+3nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D3 in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KZ5PubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50073805(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)copy SMILEScopy InChI
Affinity DataKi:  5.00E+3nMAssay Description:In vitro binding affinity at human cloned dopamine receptor D3 stably expressed in CHO cells by [3H]spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM2B5XPubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50073805(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)copy SMILEScopy InChI
Affinity DataKi:  5.00E+3nMAssay Description:Ability to displace [3H]spiperone radioligand from cloned human Dopamine receptor D3 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72J0VPubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50073805(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)copy SMILEScopy InChI
Affinity DataKi:  5.00E+3nMAssay Description:Binding affinity evaluated for the displacement of [3H]-spiperone against human dopamine receptor D3More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20Z73SGPubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50073805(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)copy SMILEScopy InChI
Affinity DataKi:  5.00E+3nMAssay Description:Binding affinity for human dopamine receptor D3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H131HWPubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50073805(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)copy SMILEScopy InChI
Affinity DataKi:  5.00E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D3 receptor by PDSP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25140RWPubMed
TargetD(3) dopamine receptor(Homo sapiens)TBA
LigandPNGBDBM50073805(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)copy SMILEScopy InChI
Affinity DataKi:  5.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50073805(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)copy SMILEScopy InChI
Affinity DataKi:  5.00E+3nMAssay Description:Inhibition of human dopamine D3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84FBZPubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center , Omaha, Nebraska 68198-6125, United States.

Curated by ChEMBL
LigandPNGBDBM50073805(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)copy SMILEScopy InChI
Affinity DataKi:  1.20E+4nMAssay Description:Inhibition of human dopamine D1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84FBZPubMed
TargetD(1A) dopamine receptor(BOVINE)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50073805(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)copy SMILEScopy InChI
Affinity DataKi:  1.20E+4nMAssay Description:Ability to displace [3H]SCH-23,390 radioligand from bovine Dopamine receptor D1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72J0VPubMed
TargetD(1A) dopamine receptor(BOVINE)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50073805(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)copy SMILEScopy InChI
Affinity DataKi:  1.20E+4nMAssay Description:Binding affinity was evaluated for the displacement of [3H]-SCH- 23390 against bovine Dopamine receptor D1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20Z73SGPubMed
TargetD(1A) dopamine receptor(BOVINE)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50073805(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)copy SMILEScopy InChI
Affinity DataKi:  1.20E+4nMAssay Description:In vitro binding affinity at human cloned dopamine receptor D1 stably expressed in CHO cells by [3H]-SCH- 23390 displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM2B5XPubMed
TargetD(1A) dopamine receptor(Sus scrofa)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50073805(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)copy SMILEScopy InChI
Affinity DataKi:  1.20E+4nMAssay Description:Displacement of [3H]SCH 23990 from dopamine receptor D1 in porcine striatal membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KZ5PubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£t Erlangen-N£rnberg

Curated by ChEMBL
LigandPNGBDBM50073805(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)copy SMILEScopy InChI
Affinity DataEC50:  16nMAssay Description:Effective concentration of compound required against human Dopamine D4.2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72J0VPubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£t Erlangen-N£rnberg

Curated by ChEMBL
LigandPNGBDBM50073805(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)copy SMILEScopy InChI
Affinity DataEC50:  12nMAssay Description:Tested for the effective concentration against CHO 10001 cells in human D4.2 receptor established in mitogenesis assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM2B5XPubMed