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SMILES Oc1cc2occ(-c3cccc(Cl)c3)c(=O)c2cc1O

InChI Key InChIKey=SXXHDZJXVFGBFC-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 106776   

TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
Universidad de Santiago de Chile

LigandPNGBDBM106776(3‐(3‐chlorophenyl)‐6,7‐dih...)copy SMILEScopy InChI
Affinity DataIC50: 280nMpH: 8.0 T: 2°CAssay Description:All reactions were carried in a volume of 2 mL stirred at 23°C with approximately 2.040 Units of 12-hLOX, 4.200 Units of 15-hLOX-1, and 6.600 Un...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ57F3PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Universidad de Santiago de Chile

LigandPNGBDBM106776(3‐(3‐chlorophenyl)‐6,7‐dih...)copy SMILEScopy InChI
Affinity DataIC50: 590nMpH: 7.5 T: 2°CAssay Description:All reactions were carried in a volume of 2 mL stirred at 23°C with approximately 2.040 Units of 12-hLOX, 4.200 Units of 15-hLOX-1, and 6.600 Un...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ57F3PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Homo sapiens (Human))
Universidad de Santiago de Chile

LigandPNGBDBM106776(3‐(3‐chlorophenyl)‐6,7‐dih...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMpH: 7.5 T: 2°CAssay Description:All reactions were carried in a volume of 2 mL stirred at 23°C with approximately 2.040 Units of 12-hLOX, 4.200 Units of 15-hLOX-1, and 6.600 Un...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ57F3PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Universidad de Santiago

LigandPNGBDBM106776(3‐(3‐chlorophenyl)‐6,7‐dih...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+5nMpH: 8.0Assay Description:Approximately 2 µg of either COX-1 or COX-2 was added to buffer containing 100 µM AA, 0.1 M Tris-HCl buffer (pH 8.0), 5 mM EDTA, 2 mM phenol, and 1 µ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ57JFPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Universidad de Santiago

LigandPNGBDBM106776(3‐(3‐chlorophenyl)‐6,7‐dih...)copy SMILEScopy InChI
Affinity DataIC50: 390nMpH: 7.3 T: 2°CAssay Description:The reactions were done in a volume of 2 mL and constantly stirred using a magnetic stir bar at room temperature (23 °C). Reactions with the crude, a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ57JFPubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Universidad de Santiago

LigandPNGBDBM106776(3‐(3‐chlorophenyl)‐6,7‐dih...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMpH: 8.0Assay Description:Approximately 2 µg of either COX-1 or COX-2 was added to buffer containing 100 µM AA, 0.1 M Tris-HCl buffer (pH 8.0), 5 mM EDTA, 2 mM phenol, and 1 µ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ57JFPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Homo sapiens (Human))
Universidad de Santiago de Chile

LigandPNGBDBM106776(3‐(3‐chlorophenyl)‐6,7‐dih...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMpH: 7.3 T: 2°CAssay Description:The reactions were done in a volume of 2 mL and constantly stirred using a magnetic stir bar at room temperature (23 °C). Reactions with the crude, a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ57JFPubMed