null
SMILES Cc1c(noc1-c1ccc(Cl)cc1)C1CCN(CCc2ccccc2)CC1
InChI Key InChIKey=QDMAKDIDFJTXEL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 16 hits for monomerid = 50050476
TargetD(4) dopamine receptor(Homo sapiens (Human))
Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center , Omaha, Nebraska 68198-6125, United States.
Curated by ChEMBL
Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center , Omaha, Nebraska 68198-6125, United States.
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Inhibition of human dopamine D4 receptorMore data for this Ligand-Target Pair
TargetD(4) dopamine receptor(Homo sapiens (Human))
Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center , Omaha, Nebraska 68198-6125, United States.
Curated by ChEMBL
Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center , Omaha, Nebraska 68198-6125, United States.
Curated by ChEMBL
Affinity DataKi: 3.5nMAssay Description:Binding affinity towards human dopamine receptor D4More data for this Ligand-Target Pair
TargetD(4) dopamine receptor(Homo sapiens (Human))
Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center , Omaha, Nebraska 68198-6125, United States.
Curated by ChEMBL
Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center , Omaha, Nebraska 68198-6125, United States.
Curated by ChEMBL
In DepthDetails
TargetD(4) dopamine receptor(Homo sapiens (Human))
Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center , Omaha, Nebraska 68198-6125, United States.
Curated by ChEMBL
Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center , Omaha, Nebraska 68198-6125, United States.
Curated by ChEMBL
Affinity DataKi: 3.5nMAssay Description:Displacement of [3H]-spiperone from human Dopamine receptor D4 expressed in HEK-293 cellsMore data for this Ligand-Target Pair
TargetD(4) dopamine receptor(Homo sapiens (Human))
Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center , Omaha, Nebraska 68198-6125, United States.
Curated by ChEMBL
Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center , Omaha, Nebraska 68198-6125, United States.
Curated by ChEMBL
Affinity DataKi: 3.5nMAssay Description:Ability to displace [3H]-spiperone from human dopamine receptor D4 (hD4) receptor stably expressed in HEK-293 cells.More data for this Ligand-Target Pair
TargetD(4) dopamine receptor(Homo sapiens (Human))
Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center , Omaha, Nebraska 68198-6125, United States.
Curated by ChEMBL
Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center , Omaha, Nebraska 68198-6125, United States.
Curated by ChEMBL
Affinity DataKi: 3.5nMAssay Description:Affinity to displace [3H]-spiperone from cloned human Dopamine receptor D4 stably expressed in HEK-393 cell linesMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center , Omaha, Nebraska 68198-6125, United States.
Curated by ChEMBL
Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center , Omaha, Nebraska 68198-6125, United States.
Curated by ChEMBL
Affinity DataKi: 480nMAssay Description:Inhibition of human dopamine D3 receptorMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center , Omaha, Nebraska 68198-6125, United States.
Curated by ChEMBL
Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center , Omaha, Nebraska 68198-6125, United States.
Curated by ChEMBL
Affinity DataKi: 770nMAssay Description:Ability to displace [3H]-spiperone from human dopamine receptor D3 (hD3) receptor stably expressed in HEK-293 cells.More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center , Omaha, Nebraska 68198-6125, United States.
Curated by ChEMBL
Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center , Omaha, Nebraska 68198-6125, United States.
Curated by ChEMBL
Affinity DataKi: 770nMAssay Description:Displacement of [3H]-spiperone from human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center , Omaha, Nebraska 68198-6125, United States.
Curated by ChEMBL
Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center , Omaha, Nebraska 68198-6125, United States.
Curated by ChEMBL
Affinity DataKi: 770nMAssay Description:Affinity to displace [3H]-spiperone from cloned human Dopamine receptor D3 (hD3) stably expressed in HEK-393 cell linesMore data for this Ligand-Target Pair
In DepthDetails
TargetD(2) dopamine receptor(Homo sapiens (Human))
Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center , Omaha, Nebraska 68198-6125, United States.
Curated by ChEMBL
Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center , Omaha, Nebraska 68198-6125, United States.
Curated by ChEMBL
Affinity DataKi: >1.70E+3nMAssay Description:Inhibition of human dopamine D2 receptorMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center , Omaha, Nebraska 68198-6125, United States.
Curated by ChEMBL
Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center , Omaha, Nebraska 68198-6125, United States.
Curated by ChEMBL
Affinity DataKi: >1.70E+3nMAssay Description:Displacement of [3H]-spiperone from human Dopamine receptor D2 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center , Omaha, Nebraska 68198-6125, United States.
Curated by ChEMBL
Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center , Omaha, Nebraska 68198-6125, United States.
Curated by ChEMBL
Affinity DataKi: >1.70E+3nMAssay Description:Ability to displace [3H]-spiperone from human dopamine receptor D2 stably expressed in CHO cells.More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center , Omaha, Nebraska 68198-6125, United States.
Curated by ChEMBL
Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center , Omaha, Nebraska 68198-6125, United States.
Curated by ChEMBL
Affinity DataKi: >1.70E+3nMAssay Description:Affinity to displace [3H]-spiperone from cloned human Dopamine receptor D2 stably expressed in CHO cell linesMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center , Omaha, Nebraska 68198-6125, United States.
Curated by ChEMBL
Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center , Omaha, Nebraska 68198-6125, United States.
Curated by ChEMBL
In DepthDetails