null
SMILES Cc1ccc(C(=O)Nc2ccc(Oc3cc4cnn(C)c4cc3-c3cn[nH]c3)c(F)c2)c(=O)n1-c1ccc(F)cc1
InChI Key InChIKey=QHADVLVFMKEIIP-UHFFFAOYSA-N
PDB links: 2 PDB IDs match this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50172078
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
University of Edinburgh
Curated by ChEMBL
University of Edinburgh
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of human full length AXL after 4 hrs followed by stimulation with human recombinant Gas6 for 15 minutes by cell based assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
University of Edinburgh
Curated by ChEMBL
University of Edinburgh
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of human full length AXL by scintillation counting method in presence of 33P-gammaATPMore data for this Ligand-Target Pair
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
University of Arkansas for Medical Sciences
Curated by ChEMBL
University of Arkansas for Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of RON (unknown origin) by FISH assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
University of Arkansas for Medical Sciences
Curated by ChEMBL
University of Arkansas for Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 4.70nMAssay Description:Inhibition of cMET (unknown origin) by FISH assayMore data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
A*STAR
Curated by ChEMBL
A*STAR
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of MNK1 (unknown origin)More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
A*STAR
Curated by ChEMBL
A*STAR
Curated by ChEMBL
Affinity DataIC50: 109nMAssay Description:Inhibition of MNK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
A*STAR
Curated by ChEMBL
A*STAR
Curated by ChEMBL
In DepthDetails
In DepthDetails
In DepthDetails
In DepthDetails
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
A*STAR
Curated by ChEMBL
A*STAR
Curated by ChEMBL