null

SMILES C1C2CC3CC1CC(C2)(C3)c1nnc2CCCCCn12

InChI Key InChIKey=VFTQRHWULYJKCI-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 50239401   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50239401(3-Adamantan-1-yl-6,7,8,9-tetrahydro-5H-[1,2,4]tria...)copy SMILEScopy InChI
Affinity DataIC50: 7.5nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9RV7PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))TBA
LigandPNGBDBM50239401(3-Adamantan-1-yl-6,7,8,9-tetrahydro-5H-[1,2,4]tria...)copy SMILEScopy InChI
Affinity DataIC50: 35nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3XBXPubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50239401(3-Adamantan-1-yl-6,7,8,9-tetrahydro-5H-[1,2,4]tria...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human 11beta-HSD2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280546BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50239401(3-Adamantan-1-yl-6,7,8,9-tetrahydro-5H-[1,2,4]tria...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280546BPubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Mus musculus (mouse))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50239401(3-Adamantan-1-yl-6,7,8,9-tetrahydro-5H-[1,2,4]tria...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mouse 11beta-HSD2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280546BPubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Amgen Inc

Curated by ChEMBL
LigandPNGBDBM50239401(3-Adamantan-1-yl-6,7,8,9-tetrahydro-5H-[1,2,4]tria...)copy SMILEScopy InChI
Affinity DataIC50: 7.5nMAssay Description:Inhibition of 11beta-HSD1 (unknown origin) expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to cortisol by SPA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X28RDPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50239401(3-Adamantan-1-yl-6,7,8,9-tetrahydro-5H-[1,2,4]tria...)copy SMILEScopy InChI
Affinity DataIC50: 7.80nMAssay Description:Inhibition of human 11beta HSD1 by SPA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP74QMPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))TBA
LigandPNGBDBM50239401(3-Adamantan-1-yl-6,7,8,9-tetrahydro-5H-[1,2,4]tria...)copy SMILEScopy InChI
Affinity DataIC50: 98nMAssay Description:Inhibition of mouse 11beta HSD1 by SPA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP74QMPubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50239401(3-Adamantan-1-yl-6,7,8,9-tetrahydro-5H-[1,2,4]tria...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human 11beta HSD2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP74QMPubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Mus musculus (mouse))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50239401(3-Adamantan-1-yl-6,7,8,9-tetrahydro-5H-[1,2,4]tria...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mouse 11beta HSD2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP74QMPubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Amgen Inc

Curated by ChEMBL
LigandPNGBDBM50239401(3-Adamantan-1-yl-6,7,8,9-tetrahydro-5H-[1,2,4]tria...)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of 11beta-HSD2 (unknown origin) expressed in CHO-K1 cells assessed as conversion of [3H]cortisol to cortisone by SPA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X28RDPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50239401(3-Adamantan-1-yl-6,7,8,9-tetrahydro-5H-[1,2,4]tria...)copy SMILEScopy InChI
Affinity DataIC50: 7.5nMAssay Description:Displacement of [3H]cortisone from human 11beta-HSD1 expressed in baculovirus-infected Sf9 cells after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9JC3PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))TBA
LigandPNGBDBM50239401(3-Adamantan-1-yl-6,7,8,9-tetrahydro-5H-[1,2,4]tria...)copy SMILEScopy InChI
Affinity DataIC50: 97nMAssay Description:Displacement of [3H]cortisone from mouse 11beta-HSD1 expressed in baculovirus-infected Sf9 cells after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9JC3PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50239401(3-Adamantan-1-yl-6,7,8,9-tetrahydro-5H-[1,2,4]tria...)copy SMILEScopy InChI
Affinity DataIC50: 7.80nMAssay Description:Inhibition of human 11-beta-HSD1 by SPA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H99625PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))TBA
LigandPNGBDBM50239401(3-Adamantan-1-yl-6,7,8,9-tetrahydro-5H-[1,2,4]tria...)copy SMILEScopy InChI
Affinity DataIC50: 98nMAssay Description:Inhibition of mouse 11-beta-HSD1 by SPA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H99625PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50239401(3-Adamantan-1-yl-6,7,8,9-tetrahydro-5H-[1,2,4]tria...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human 11-beta-HSD2 by SPA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H99625PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Mus musculus (mouse))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50239401(3-Adamantan-1-yl-6,7,8,9-tetrahydro-5H-[1,2,4]tria...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mouse 11-beta-HSD2 by SPA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H99625PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50239401(3-Adamantan-1-yl-6,7,8,9-tetrahydro-5H-[1,2,4]tria...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3XBXPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50239401(3-Adamantan-1-yl-6,7,8,9-tetrahydro-5H-[1,2,4]tria...)copy SMILEScopy InChI
Affinity DataIC50: 7.70nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3XBXPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))TBA
LigandPNGBDBM50239401(3-Adamantan-1-yl-6,7,8,9-tetrahydro-5H-[1,2,4]tria...)copy SMILEScopy InChI
Affinity DataIC50: 97nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9RV7PubMed