null
SMILES [#6]-n1cc(-[#7]-[#6](=O)-c2cc(-[#7]-[#6](=O)-[#6]\[#7]=[#6](\[#7])-[#7])cn2-[#6])cc1-[#6](=O)-[#7]-[#6]-[#6]-[#6](-[#7])=[#7]
InChI Key InChIKey=IDBIFFKSXLYUOT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50055660
TargetDNA helicase [35-727](Plasmodium falciparum)
International Centre for Genetic Engineering and Biotechnology
International Centre for Genetic Engineering and Biotechnology
Affinity DataIC50: 3.10E+3nMpH: 8.0 T: 2°CAssay Description:The hydrolysis of ATP catalyzed by PfUDN was assayed by measuring the formation of Pi from [γ-32P] ATP. The reaction mixture of 10 μl conta...More data for this Ligand-Target Pair
TargetDNA helicase [35-727](Plasmodium falciparum)
International Centre for Genetic Engineering and Biotechnology
International Centre for Genetic Engineering and Biotechnology
Affinity DataIC50: 4.70E+3nMpH: 8.0 T: 2°CAssay Description:Helicase assay was demonstrated using the purified fraction of PfUDN. The specially designed partial duplex substrate consisted of a 32P-labelled 47-...More data for this Ligand-Target Pair
Affinity DataIC50: 6.20E+4nMAssay Description:Inhibit supercoil relaxation property of topoisomerase I.More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Quantities of 0.2 mL of examined preparation (as control, 0.15 M NaCl), buffer, and 0.1 mL of enzyme solution were mixed together. The mixture was in...More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+4nMAssay Description:Quantities of 0.2 mL of examined preparation (as control, 0.15 M NaCl), buffer, and 0.1 mL of enzyme solution were mixed together. The mixture was in...More data for this Ligand-Target Pair