null

SMILES Nc1ncnc2n(cc(-c3cccc(OCc4ccccc4)c3)c12)[C@H]1C[C@@H](C1)N1CCC1

InChI Key InChIKey=USVCWSAJUAARAL-MEMLXQNLSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50296348   

TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50296348(7-(3-(azetidin-1-yl)cyclobutyl)-5-(3-(benzyloxy)ph...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BCR-ABL p210More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84CTDPubMed
TargetInsulin receptor(Mus musculus)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50296348(7-(3-(azetidin-1-yl)cyclobutyl)-5-(3-(benzyloxy)ph...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of insulin receptor-mediated proliferation of mouse NIH/3T3 cells after 48 hrs by MTT assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84CTDPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50296348(7-(3-(azetidin-1-yl)cyclobutyl)-5-(3-(benzyloxy)ph...)copy SMILEScopy InChI
Affinity DataIC50: 86nMAssay Description:Inhibition of IGF1R by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84CTDPubMed
TargetInsulin-like growth factor 1 receptor(Mus musculus)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50296348(7-(3-(azetidin-1-yl)cyclobutyl)-5-(3-(benzyloxy)ph...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of IGF1R-mediated proliferation of mouse NIH/3T3 cells after 48 hrs by MTT assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84CTDPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50296348(7-(3-(azetidin-1-yl)cyclobutyl)-5-(3-(benzyloxy)ph...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HER1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84CTDPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50296348(7-(3-(azetidin-1-yl)cyclobutyl)-5-(3-(benzyloxy)ph...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of c-KITMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84CTDPubMed
TargetInsulin receptor(Homo sapiens (Human))
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50296348(7-(3-(azetidin-1-yl)cyclobutyl)-5-(3-(benzyloxy)ph...)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of insulin receptor by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84CTDPubMed