null

SMILES [#6]-[#6]-[#6@H](-[#6])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(-[#8])cc1)-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6]-[#7]-1-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6]-[#7]-1-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(-[#8])cc1)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6](=O)-[#7]-1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#6])-[#6])-[#6](-[#8])=O

InChI Key InChIKey=PCJGZPGTCUMMOT-ISULXFBGSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 41 hits for monomerid = 50130880   

TargetNeurotensin receptor type 1(MOUSE)
TBA

Curated by ChEMBL
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)copy SMILEScopy InChI
Affinity DataKi:  0.170nMAssay Description:Concentration producing half maximal inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptor in neonatal mouse whole brain (minus cereb...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8DDX
TargetNeurotensin receptor type 1(Homo sapiens (Human))
Universit£ degli Studi di Siena

Curated by ChEMBL
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)copy SMILEScopy InChI
Affinity DataKi:  0.270nMAssay Description:Binding affinity to human NTS1 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3NKCPubMed
TargetNeurotensin receptor type 1(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:Displacement of [125I]neurotensin from rat NTS1 receptor expressed in CHO-K1 cells by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP04C6PubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
Universit£ degli Studi di Siena

Curated by ChEMBL
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)copy SMILEScopy InChI
Affinity DataKi:  1.20nMAssay Description:Binding affinity to human neurotensin receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF30GNPubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
Universit£ degli Studi di Siena

Curated by ChEMBL
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)copy SMILEScopy InChI
Affinity DataKi:  1.64nMAssay Description:Displacement of [125I]I-Tyr(3)NT from human NTR1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z9DPubMed
TargetNeurotensin receptor type 1(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)copy SMILEScopy InChI
Affinity DataKi:  1.70nMAssay Description:Displacement of [125L]NT from rat neurotensin receptor type 1 expressed in CHOK1 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90B9GPubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
Universit£ degli Studi di Siena

Curated by ChEMBL
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)copy SMILEScopy InChI
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]NT(8-13) from wild type human NTR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1T0ZPubMed
TargetNeurotensin(GUINEA PIG)
Hôpital Saint-Antoine

Curated by PDSP Ki Database
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)copy SMILEScopy InChI
Affinity DataKi:  2.80nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GB22J5PubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
Universit£ degli Studi di Siena

Curated by ChEMBL
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)copy SMILEScopy InChI
Affinity DataKi:  3.30nMAssay Description:Displacement of [125I]Tyr3-neurotensin from human recombinant NTS1 stably expressed in CHO-K1 cell membranes incubated for 60 mins by gamma counter a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS318CPubMed
TargetNeurotensin receptor type 2(Homo sapiens (Human))TBA
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)copy SMILEScopy InChI
Affinity DataKi:  4.10nMAssay Description:Displacement of [125I]Tyr3-neurotensin from human recombinant NTS2 stably expressed in human 1321N1 cell membranes incubated for 60 mins by gamma cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS318CPubMed
TargetNeurotensin receptor type 2(Homo sapiens (Human))TBA
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)copy SMILEScopy InChI
Affinity DataKi:  4.90nMAssay Description:Displacement of [3H]NT from human NTS2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8FVGPubMed
TargetNeurotensin receptor type 2(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)copy SMILEScopy InChI
Affinity DataKi:  19nMAssay Description:Displacement of [125I]NT at rat NTS2 overexpressed in CHOK1 cells after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XJDPubMed
TargetNeurotensin receptor type 2(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)copy SMILEScopy InChI
Affinity DataKi:  21nMAssay Description:Displacement of [125L]NT from rat neurotensin receptor type 2 expressed in CHOK1 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90B9GPubMed
TargetNeurotensin receptor type 2(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)copy SMILEScopy InChI
Affinity DataKi:  28nMAssay Description:Displacement of [125I]neurotensin from rat NTS2 receptor expressed in CHO-K1 cells by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP04C6PubMed
TargetNeurotensin(GUINEA PIG)
Hôpital Saint-Antoine

Curated by PDSP Ki Database
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)copy SMILEScopy InChI
Affinity DataKi:  51nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GB22J5PubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
Universit£ degli Studi di Siena

Curated by ChEMBL
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)copy SMILEScopy InChI
Affinity DataKd:  0.590nMAssay Description:Displacement of [3H]neurotensin from human NTS1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8FVGPubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
Universit£ degli Studi di Siena

Curated by ChEMBL
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Binding affinity towards neurotensin receptor in membranes prepared from HT-29 cell line, relative to [111In]-labeled neurotensin peptideMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222VHRPubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
Universit£ degli Studi di Siena

Curated by ChEMBL
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)copy SMILEScopy InChI
Affinity DataIC50: 0.620nMAssay Description:Displacement of [125I]Tyr3-NT from human NTS1R expressed in HT29 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22808DPPubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
Universit£ degli Studi di Siena

Curated by ChEMBL
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)copy SMILEScopy InChI
Affinity DataIC50: 0.460nMAssay Description:Displacement of [125I]Tyr3-NT from human NTS1R expressed in WiDr cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22808DPPubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
Universit£ degli Studi di Siena

Curated by ChEMBL
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)copy SMILEScopy InChI
Affinity DataKd:  0.510nMAssay Description:Displacement of [3H]neurotensin from human NTS1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068H9PubMed
TargetSortilin(Homo sapiens (Human))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)copy SMILEScopy InChI
Affinity DataIC50: 360nMAssay Description:Displacement of [3H]-neurotensin from human sortilin incubated 30 mins prior to [3H]-neurotensin addition measured after 6 hrs by scintillation proxi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN39BBPubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
Universit£ degli Studi di Siena

Curated by ChEMBL
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)copy SMILEScopy InChI
Affinity DataIC50: 0.240nMAssay Description:Binding affinity to NTS1 receptor (unknown origin) by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87C5QPubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
Universit£ degli Studi di Siena

Curated by ChEMBL
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)copy SMILEScopy InChI
Affinity DataIC50: 0.330nMAssay Description:Binding affinity to human NTS1 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3NKCPubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
Universit£ degli Studi di Siena

Curated by ChEMBL
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)copy SMILEScopy InChI
Affinity DataIC50: 0.490nMAssay Description:Displacement of [125I]Tyr3-neurotensin from human recombinant NTS1 receptor expressed in CHO cells measured after 60 mins by scintillation counting m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9S3SPubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
Universit£ degli Studi di Siena

Curated by ChEMBL
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)copy SMILEScopy InChI
Affinity DataIC50: 0.160nMMore data for this Ligand-Target Pair
In DepthDetails
TargetNeurotensin receptor type 1(Homo sapiens (Human))
Universit£ degli Studi di Siena

Curated by ChEMBL
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)copy SMILEScopy InChI
Affinity DataIC50: 6.03nMAssay Description:Antagonist activity at human NTS1 receptor expressed in CHOK1 cells assessed as inhibition of intracellular calcium elevation pretreated 30 mins befo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X57S8PubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
Universit£ degli Studi di Siena

Curated by ChEMBL
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)copy SMILEScopy InChI
Affinity DataEC50:  310nMAssay Description:Agonist activity at human NTS1 receptor expressed in CHOK1 cells assessed as increase in intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X57S8PubMed
TargetNeurotensin receptor type 2(Homo sapiens (Human))TBA
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMMore data for this Ligand-Target Pair
In DepthDetails
TargetNeurotensin receptor type 1(Homo sapiens (Human))
Universit£ degli Studi di Siena

Curated by ChEMBL
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)copy SMILEScopy InChI
Affinity DataEC50:  0.230nMAssay Description:Agonist activity at NTR1 (unknown origin) expressed in CHOK1 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RVQPubMed
TargetNeurotensin receptor type 1(MOUSE)
TBA

Curated by ChEMBL
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)copy SMILEScopy InChI
Affinity DataEC50:  2nMAssay Description:Agonist activity at NTR1 in mouse N1E-115 cells assessed as increase in intracellular calcium concentrationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z9DPubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
Universit£ degli Studi di Siena

Curated by ChEMBL
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)copy SMILEScopy InChI
Affinity DataEC50:  2nMAssay Description:Agonist activity at human NTR1 assessed as increase in intracellular calcium concentrationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z9DPubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
Universit£ degli Studi di Siena

Curated by ChEMBL
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)copy SMILEScopy InChI
Affinity DataEC50:  1.98nMAssay Description:Agonist activity at NTR1 in human HT-29 cells assessed as increase in intracellular calcium concentration by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z9DPubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
Universit£ degli Studi di Siena

Curated by ChEMBL
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)copy SMILEScopy InChI
Affinity DataIC50: 2.19nMAssay Description:Displacement of [125I]I-Tyr(3)NT from human NTR1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z9DPubMed
TargetNeurotensin receptor type 2(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)copy SMILEScopy InChI
Affinity DataEC50: >100nMAssay Description:Agonist activity at rat neurotensin receptor type 2 expressed in CHOK1 cells assessed as increase in calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90B9GPubMed
TargetNeurotensin receptor type 2(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Antagonist activity at rat neurotensin receptor type 2 expressed in CHOK1 cells assessed as inhibition of SR142948a-induced calcium release by FLIPR ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90B9GPubMed
TargetNeurotensin receptor type 2(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)copy SMILEScopy InChI
Affinity DataIC50: 114nMAssay Description:Antagonist activity at rat NTS2 receptor expressed in CHO-K1 cells assessed as inhibition of SR142948a-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP04C6PubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
Universit£ degli Studi di Siena

Curated by ChEMBL
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)copy SMILEScopy InChI
Affinity DataEC50:  1.60nMAssay Description:Agonist activity at human NTS1 receptor expressed in HEK293 cells assessed as inhibition of constitutive activity on MAPK-mediated luciferase activit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8FVGPubMed
TargetNeurotensin receptor type 2(Homo sapiens (Human))TBA
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)copy SMILEScopy InChI
Affinity DataEC50:  110nMAssay Description:Agonist activity at human NTS2 receptor expressed in HEK293 cells assessed as inhibition of constitutive activity on MAPK-mediated luciferase activit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8FVGPubMed
TargetNeurotensin receptor type 1(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)copy SMILEScopy InChI
Affinity DataEC50:  0.0400nMAssay Description:Agonist activity at rat NTS1 stably expressed in CHOK1 cells assessed as induction of calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XJDPubMed
TargetNeurotensin receptor type 2(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Antagonist activity at rat NTS2 stably expressed in CHOK1 cells assessed as inhibition of SR142948a-induced calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XJDPubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
Universit£ degli Studi di Siena

Curated by ChEMBL
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)copy SMILEScopy InChI
Affinity DataIC50: 0.490nMAssay Description:Displacement of [125I]Tyr3-neurotensin from human recombinant NT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JS7PubMed