null

SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)NO)c2c1

InChI Key InChIKey=AJRNYCDWNITGHF-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50012893   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50012893(2-[1-(4-Chloro-benzoyl)-5-methoxy-2-methyl-1H-indo...)copy SMILEScopy InChI
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of 5-lipoxygenase in intact RBL-1 cell lineMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4HGZPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50012893(2-[1-(4-Chloro-benzoyl)-5-methoxy-2-methyl-1H-indo...)copy SMILEScopy InChI
Affinity DataIC50: 7.50E+3nMAssay Description:Tested for inhibition of 5-Lipoxygenase (ARBL) in calcium-stimulated rat basophillic leukemia cells(RBL-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TD9X9T
TargetProstaglandin G/H synthase 1/2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50012893(2-[1-(4-Chloro-benzoyl)-5-methoxy-2-methyl-1H-indo...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Tested for inhibition of cyclooxygenase (ARBC) in calcium-stimulated rat basophilic leukemia cells(RBL-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TD9X9T
TargetProstaglandin G/H synthase 1/2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50012893(2-[1-(4-Chloro-benzoyl)-5-methoxy-2-methyl-1H-indo...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase in intact RBL-1 cell lineMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4HGZPubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
NitroMed, Inc.

Curated by ChEMBL
LigandPNGBDBM50012893(2-[1-(4-Chloro-benzoyl)-5-methoxy-2-methyl-1H-indo...)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4K9JPubMed