null

SMILES COc1cccc(c1)C#CCO\N=C1/CN2CCC1C2

InChI Key InChIKey=FXBXWJPMXQHOGD-WUKNDPDISA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50065223   

TargetMuscarinic acetylcholine receptor M2(RAT)
Novo Nordisk A/S

Curated by ChEMBL
LigandPNGBDBM50065223(1-Aza-bicyclo[2.2.1]heptan-3-one O-[3-(3-methoxy-p...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:In vitro Muscarinic acetylcholine receptor M2 binding was evaluated in rat brain membranes by using [3H]- Oxo-MMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD12BTPubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Novo Nordisk A/S

Curated by ChEMBL
LigandPNGBDBM50065223(1-Aza-bicyclo[2.2.1]heptan-3-one O-[3-(3-methoxy-p...)copy SMILEScopy InChI
Affinity DataEC50:  7.12E+3nMAssay Description:Stimulation of phosphoinositol hydrolysis in the mouse fibroblast cell line A9L-M1 expressing Muscarinic acetylcholine receptor M1.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD12BTPubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Novo Nordisk A/S

Curated by ChEMBL
LigandPNGBDBM50065223(1-Aza-bicyclo[2.2.1]heptan-3-one O-[3-(3-methoxy-p...)copy SMILEScopy InChI
Affinity DataEC50:  2.67E+4nMAssay Description:Compound was tested for its potency towards Muscarinic acetylcholine receptor M2 by inhibiting forskolin induced c-AMP formation in CHO-M2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD12BTPubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Novo Nordisk A/S

Curated by ChEMBL
LigandPNGBDBM50065223(1-Aza-bicyclo[2.2.1]heptan-3-one O-[3-(3-methoxy-p...)copy SMILEScopy InChI
Affinity DataIC50: 5.20E+4nMAssay Description:Binding affinity of [3H]-QNB to CHO cells expressing human Muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6XKKPubMed
LigandPNGBDBM50065223(1-Aza-bicyclo[2.2.1]heptan-3-one O-[3-(3-methoxy-p...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Binding affinity towards muscarinic receptor using [3H]cis-methyldioxolane (CMD) to label agonist sites in membrane preparations from rat neocortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2736T2X
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Novo Nordisk A/S

Curated by ChEMBL
LigandPNGBDBM50065223(1-Aza-bicyclo[2.2.1]heptan-3-one O-[3-(3-methoxy-p...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+3nMAssay Description:Stimulation of phosphoinositide hydrolysis in A9L cells expressing human m1 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M08GKPubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Novo Nordisk A/S

Curated by ChEMBL
LigandPNGBDBM50065223(1-Aza-bicyclo[2.2.1]heptan-3-one O-[3-(3-methoxy-p...)copy SMILEScopy InChI
Affinity DataEC50:  2.80E+4nMAssay Description:Stimulation of cAMP in CHO cells expressing human m2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M08GKPubMed
LigandPNGBDBM50065223(1-Aza-bicyclo[2.2.1]heptan-3-one O-[3-(3-methoxy-p...)copy SMILEScopy InChI
Affinity DataIC50: 167nMAssay Description:Binding affinity against muscarinic receptor in rat brain membranes using oxotremorine-M as ligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M08GKPubMed
LigandPNGBDBM50065223(1-Aza-bicyclo[2.2.1]heptan-3-one O-[3-(3-methoxy-p...)copy SMILEScopy InChI
Affinity DataIC50: 6.93E+3nMAssay Description:Binding affinity towards muscarinic receptor using [3H]quinuclidinyl benzilate (QNB) to label antagonist sites in membrane preparations from rat neoc...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2736T2X
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Novo Nordisk A/S

Curated by ChEMBL
LigandPNGBDBM50065223(1-Aza-bicyclo[2.2.1]heptan-3-one O-[3-(3-methoxy-p...)copy SMILEScopy InChI
Affinity DataIC50: 7.68E+3nMAssay Description:Binding affinity of [3H]-QNB to CHO cells expressing human Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6XKKPubMed