null
SMILES OC(=O)P(O)(O)=O
InChI Key InChIKey=ZJAOAACCNHFJAH-UHFFFAOYSA-N
PDB links: 8 PDB IDs match this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 20 hits for monomerid = 50011181
Affinity DataKi: 8.20E+5nMAssay Description:Binding affinity towards human membrane associated carbonic anhydrase IVMore data for this Ligand-Target Pair
Affinity DataKi: 2.21E+6nMAssay Description:Binding affinity owards recombinant human transmembrane carbonic anhydrase IXMore data for this Ligand-Target Pair
Affinity DataKi: 1.42E+7nMAssay Description:Binding affinity towards human cytosolic carbonic anhydrase IIMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
Université Montpellier II
Curated by ChEMBL
Université Montpellier II
Curated by ChEMBL
Affinity DataKi: 4.17E+7nMAssay Description:Binding affinity towards recombinant human mitochondrial carbonic anhydrase VMore data for this Ligand-Target Pair
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase E89T mutant assessed as inhibition of DNA primer extension using [8-3H(N)]-dATP by scintillation p...More data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase M184V mutant assessed as inhibition of DNA primer extension using [8-3H(N)]-dATP by scintillation ...More data for this Ligand-Target Pair
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Pharmacia Corporation
Curated by ChEMBL
Pharmacia Corporation
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMpH: 7.5Assay Description:Inhibition of human alpha DNA polymerase (95 uL) activity in a solution containg 6.4 mM HEPES (pH 7.5) upon incubation for 12 minutes at 26 degrees C...More data for this Ligand-Target Pair
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pharmacia Corporation
Curated by ChEMBL
Pharmacia Corporation
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMpH: 7.5Assay Description:Inhibition of human cytomegalovirus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 d...More data for this Ligand-Target Pair
TargetDNA polymerase delta catalytic subunit(Homo sapiens (Human))
Pharmacia Corporation
Curated by ChEMBL
Pharmacia Corporation
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMpH: 7.5Assay Description:Inhibition of human delta DNA polymerase (95 uL) activity in a solution containg 6.4 mM HEPES (pH 7.5) upon incubation for 12 minutes at 26 degrees C...More data for this Ligand-Target Pair
TargetDNA polymerase catalytic subunit(Varicella-zoster virus (strain Dumas) (HHV-3) (Hum...)
Pharmacia Corporation
Curated by ChEMBL
Pharmacia Corporation
Curated by ChEMBL
Affinity DataIC50: 280nMpH: 7.5Assay Description:Inhibition of Varicella-Zoster virus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 ...More data for this Ligand-Target Pair
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pharmacia Corporation
Curated by ChEMBL
Pharmacia Corporation
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of HCMV DNA polymerase by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of HIV1 reverse transcriptase p66/p51 polymerase using PPT57 DNA/Cy5-labeled PPT24 as template/primer preincubated for 10 mins followed by...More data for this Ligand-Target Pair
Affinity DataKd: 400nMAssay Description:Binding affinity to HIV1 reverse transcriptase p66/p51-polypurine tract primer complex in presence of Mg2+ ions by band shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.39E+4nMAssay Description:Binding affinity to HIV1 reverse transcriptase p66/p51-polypurine tract primer complex in absence of Mg2+ ions by band shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of HIV1 RT mediated DNA-dependent DNA synthesis initiation using RNA/DNAM duplex primed substrate by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase K65R mutant assessed as inhibition of DNA primer extension using [8-3H(N)]-dATP by scintillation p...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as inhibition of DNA primer extension using [8-3H(N)]-dATP by scintillation proximity ass...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of HIV1 RT mediated DNA-dependent DNA synthesis initiation using RNA PPT primed substrate by scintillation proximity assayMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Instituto de Química Médica (C.S.I.C.)
Curated by ChEMBL
Instituto de Química Médica (C.S.I.C.)
Curated by ChEMBL
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibitory concentration against wild type HIV-1 reverse transcriptase (RT) using poly rC.dG as the template or primerMore data for this Ligand-Target Pair
3D Structure (crystal)TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Instituto de Química Médica (C.S.I.C.)
Curated by ChEMBL
Instituto de Química Médica (C.S.I.C.)
Curated by ChEMBL
Affinity DataIC50: 5.60E+4nMAssay Description:Inhibitory concentration against wild type HIV-1/138Lys reverse transcriptase (RT) using [3H]dGTP as a radioligandMore data for this Ligand-Target Pair