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SMILES CC(Cc1ccccc1)NCCC(c1ccccc1)c1ccccc1

InChI Key InChIKey=IFFPICMESYHZPQ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50017723   

LigandPNGBDBM50017723((3,3-Diphenyl-propyl)-(1-methyl-2-phenyl-ethyl)-am...)copy SMILEScopy InChI
Affinity DataKi:  320nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5KP4PubMed
LigandPNGBDBM50017723((3,3-Diphenyl-propyl)-(1-methyl-2-phenyl-ethyl)-am...)copy SMILEScopy InChI
Affinity DataKi:  384nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5KP4PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50017723((3,3-Diphenyl-propyl)-(1-methyl-2-phenyl-ethyl)-am...)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Inhibition of potassium current (Ikr) measured using whole-cell patch clamp experiments in HEK-293 cells stable transfected with hERG cDNAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NP264FPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50017723((3,3-Diphenyl-propyl)-(1-methyl-2-phenyl-ethyl)-am...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z321T8PubMed
TargetCalmodulin(Bos taurus)
Universit£ degli Studi di Bari 'Aldo Moro'

Curated by ChEMBL
LigandPNGBDBM50017723((3,3-Diphenyl-propyl)-(1-methyl-2-phenyl-ethyl)-am...)copy SMILEScopy InChI
Affinity DataKd:  1.80E+3nMAssay Description:Binding affinity to bovine brain CaM by FTPFACE analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2424ZPubMedDrugBank
TargetCalmodulin(Bos taurus)
Universit£ degli Studi di Bari 'Aldo Moro'

Curated by ChEMBL
LigandPNGBDBM50017723((3,3-Diphenyl-propyl)-(1-methyl-2-phenyl-ethyl)-am...)copy SMILEScopy InChI
Affinity DataKd:  500nMAssay Description:Binding affinity to dansylated bovine testes CaM by fluorescence analysis in presence of calcium2+More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2424ZPubMedDrugBank
TargetCalmodulin(Bos taurus)
Universit£ degli Studi di Bari 'Aldo Moro'

Curated by ChEMBL
LigandPNGBDBM50017723((3,3-Diphenyl-propyl)-(1-methyl-2-phenyl-ethyl)-am...)copy SMILEScopy InChI
Affinity DataEC50:  2.40E+3nMAssay Description:Binding affinity to dansylated bovine brain CaM assessed as half maximal increase in fluorescence by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2424ZPubMedDrugBank
LigandPNGBDBM50017723((3,3-Diphenyl-propyl)-(1-methyl-2-phenyl-ethyl)-am...)copy SMILEScopy InChI
Affinity DataKd:  209nMAssay Description:Compound was tested in vitro for inhibitory activity against Herpes Simplex Virus type 2 ribonucleotide reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29C70MX
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Cavia porcellus)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50017723((3,3-Diphenyl-propyl)-(1-methyl-2-phenyl-ethyl)-am...)copy SMILEScopy InChI
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of calcium current (ICaL) measured using whole-cell patch clamp experiments in isolated guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NP264FPubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50017723((3,3-Diphenyl-propyl)-(1-methyl-2-phenyl-ethyl)-am...)copy SMILEScopy InChI
Affinity DataIC50: 2.52E+3nMAssay Description:Inhibition of sodium current measured using whole-cell patch clamp experiments in HEK-293 cells stably transfected with hNaV1.5 cDNAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NP264FPubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Cavia porcellus)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50017723((3,3-Diphenyl-propyl)-(1-methyl-2-phenyl-ethyl)-am...)copy SMILEScopy InChI
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of L-type calcium channel measured using whole-cell patch clamp in guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79D5CPubMed