null

SMILES C[C@](O)(CI)C(=O)Nc1ccc(C#N)c(c1)C(F)(F)F

InChI Key InChIKey=KMBKIAPXINYEHM-NSHDSACASA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 18700   

TargetAndrogen receptor(Rattus norvegicus (Rat))
University of Tennessee at Memphis

LigandPNGBDBM18700((2R)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydro...)copy SMILEScopy InChI
Affinity DataKi:  2.79nM ΔG°:  -10.8kcal/mole EC50:  500nMpH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930RFCPubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
University of Tennessee at Memphis

LigandPNGBDBM18700((2R)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydro...)copy SMILEScopy InChI
Affinity DataKi:  2.80nMAssay Description:Inhibition of [3H]mibolerone binding to cytosolic androgen receptor of rat ventral prostateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1PBDPubMed