null

SMILES O=C1[C@H](CCN1Cc1cc2ccncc2[nH]1)NS(=O)(=O)c1cc2ncccc2s1

InChI Key InChIKey=PLXOQMHGHDZMSX-AWEZNQCLSA-N

PDB links: 1 PDB ID matches this monomer. 1 PDB ID contains inhibitors having a similarity of 90% to this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 14057   

TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharma

LigandPNGBDBM14057(N-[(3S)-1-(4,7-diazabicyclo[4.3.0]nona-2,4,8,10-te...)copy SMILEScopy InChI
Affinity DataKi:  18nM ΔG°:  -10.5kcal/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharma

LigandPNGBDBM14057(N-[(3S)-1-(4,7-diazabicyclo[4.3.0]nona-2,4,8,10-te...)copy SMILEScopy InChI
Affinity DataKi:  18nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
TargetSerine protease 1(Bos taurus (bovine))
Aventis Pharma

LigandPNGBDBM14057(N-[(3S)-1-(4,7-diazabicyclo[4.3.0]nona-2,4,8,10-te...)copy SMILEScopy InChI
Affinity DataKi: >2.90E+3nM ΔG°: >-7.47kcal/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7DHPPubMed
TargetProthrombin(Homo sapiens (Human))
Aventis Pharma

LigandPNGBDBM14057(N-[(3S)-1-(4,7-diazabicyclo[4.3.0]nona-2,4,8,10-te...)copy SMILEScopy InChI
Affinity DataKi: >4.00E+3nM ΔG°: >-7.28kcal/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7DHPPubMed