null

SMILES COC1=C(OC)C(=O)C(CCCCCCCCCCO)=C(C)C1=O

InChI Key InChIKey=JGPMMRGNQUBGND-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50505498   

TargetNAD-dependent protein deacetylase(Schistosoma mansoni)
University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50505498(CHEBI:31687 | Idebenone | Raxone)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of recombinant Schistosoma mansoni sirtuin 2 (21 to 322 residues) expressed in Escherichia coli BL21(DE3) cells using ZMAL as substrate af...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25142HKPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Vellore Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50505498(CHEBI:31687 | Idebenone | Raxone)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate measured after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5S90PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Vellore Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50505498(CHEBI:31687 | Idebenone | Raxone)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate measured after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5S90PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50505498(CHEBI:31687 | Idebenone | Raxone)copy SMILEScopy InChI
Affinity DataIC50: 1.54E+4nMAssay Description:Inhibition of N-terminal His6 tagged human sirtuin 2 (25 to 389 residues) using Cbz-Lys(acetyl)-AMC as substrate after 4 hrs in presence of NAD+ by h...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25142HKPubMed