null

SMILES Fc1ccc(Cc2ccc(o2)C(=O)CC(=O)c2nnc[nH]2)cc1

InChI Key InChIKey=RQQWCYPROZEXIC-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 23398   

TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gilead Sciences Inc.

LigandPNGBDBM23398((2Z)-1-{5-[(4-fluorophenyl)methyl]furan-2-yl}-3-hy...)copy SMILEScopy InChI
Affinity DataIC50: 46nMpH: 7.3 T: 2°CAssay Description:In the 3-end joining assay, the biotinylated donor DNA was bound to streptavidin-coated plates, and integrase was added to each well to allow process...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2707ZQFPubMed
TargetIntegrase(Human immunodeficiency virus 1)
Università di Messina

Curated by ChEMBL
LigandPNGBDBM23398((2Z)-1-{5-[(4-fluorophenyl)methyl]furan-2-yl}-3-hy...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Strand transfer inhibitory activity against HIV-1 integraseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6BR1PubMed
TargetIntegrase(Human immunodeficiency virus 1)
Università di Messina

Curated by ChEMBL
LigandPNGBDBM23398((2Z)-1-{5-[(4-fluorophenyl)methyl]furan-2-yl}-3-hy...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibitory concentration against human immunodeficiency virus type 1 integraseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5MPJPubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM23398((2Z)-1-{5-[(4-fluorophenyl)methyl]furan-2-yl}-3-hy...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Concentration required to inhibit catalytic activity of human immuno deficiency virus type 1 integraseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4PD6PubMed