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SMILES Oc1ccccc1\C=C/c1ccc2ccccc2n1

InChI Key InChIKey=NXNDEWNGCMCWMA-BENRWUELSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50271179   

TargetEEF1AKMT4-ECE2 readthrough transcript protein(Homo sapiens (Human))
Icahn School of Medicine at Mount Sinai

LigandPNGBDBM50271179(2-(2-(quinolin-2-yl)vinyl)phenol | CHEMBL487942 | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMpH: 5.5Assay Description:Recombinant ECE2 (32.5 ng) with a specific activity of 12 pmol/min/μg protein was generated as described previously. Secreted soluble recombinan...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6XBFPubMed
TargetEEF1AKMT4-ECE2 readthrough transcript protein(Homo sapiens (Human))
Icahn School of Medicine at Mount Sinai

LigandPNGBDBM50271179(2-(2-(quinolin-2-yl)vinyl)phenol | CHEMBL487942 | ...)copy SMILEScopy InChI
Affinity DataIC50: 4.63E+3nMAssay Description:Reduction of recombinant ECE2 (unknown origin) activity measured by McaBk2 fluorescent substrate hydrolysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319VN5PubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Icahn School of Medicine at Mount Sinai

LigandPNGBDBM50271179(2-(2-(quinolin-2-yl)vinyl)phenol | CHEMBL487942 | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMpH: 7.4Assay Description:Recombinant ECE2 (32.5 ng) with a specific activity of 12 pmol/min/μg protein was generated as described previously. Secreted soluble recombinan...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6XBFPubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Icahn School of Medicine at Mount Sinai

LigandPNGBDBM50271179(2-(2-(quinolin-2-yl)vinyl)phenol | CHEMBL487942 | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMpH: 5.5Assay Description:Recombinant ECE2 (32.5 ng) with a specific activity of 12 pmol/min/μg protein was generated as described previously. Secreted soluble recombinan...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6XBFPubMed