null

SMILES Oc1ccc(CCNCCS(=O)(=O)CCCOCCc2ccccc2)c2sc(=O)[nH]c12

InChI Key InChIKey=DBCKRBGYGMVSTI-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50128690   

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50128690(4-Hydroxy-7-{2-[2-(3-phenethyloxy-propane-1-sulfon...)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Binding affinity to human beta2-adrenoceptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73G09PubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50128690(4-Hydroxy-7-{2-[2-(3-phenethyloxy-propane-1-sulfon...)copy SMILEScopy InChI
Affinity DataKi:  3.92E+3nMAssay Description:Binding affinity to human beta1-adrenoceptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73G09PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50128690(4-Hydroxy-7-{2-[2-(3-phenethyloxy-propane-1-sulfon...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:In vitro inhibitory activity was determined against human Phosphodiesterase 4 isoform using a construct representing the common region of spliced var...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X5756PubMed
TargetBile salt export pump(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50128690(4-Hydroxy-7-{2-[2-(3-phenethyloxy-propane-1-sulfon...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro displacement of [3H]ICS-205-930 from 5-hydroxytryptamine 3 receptor in cultured NG-108-15 rat glioma cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP488MPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50128690(4-Hydroxy-7-{2-[2-(3-phenethyloxy-propane-1-sulfon...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Binding affinity to dopamine 2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3NS2PubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50128690(4-Hydroxy-7-{2-[2-(3-phenethyloxy-propane-1-sulfon...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to adrenergic beta1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3NS2PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50128690(4-Hydroxy-7-{2-[2-(3-phenethyloxy-propane-1-sulfon...)copy SMILEScopy InChI
Affinity DataEC50:  4.5nMAssay Description:Agonist activity at human dopamine D2 receptor expressed in CHO cells assessed as increase in GTPgamma35S binding by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73G09PubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50128690(4-Hydroxy-7-{2-[2-(3-phenethyloxy-propane-1-sulfon...)copy SMILEScopy InChI
Affinity DataEC50:  0.631nMAssay Description:Agonist activity at human beta2 adrenoceptor expressed in H292 cells assessed as increase in cAMP accumulation after 60 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5H90PubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50128690(4-Hydroxy-7-{2-[2-(3-phenethyloxy-propane-1-sulfon...)copy SMILEScopy InChI
Affinity DataEC50:  0.631nMAssay Description:Agonist activity at human adrenergic beta2 receptor expressed in H292 cells assessed as stimulation of cAMP accumulation after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3NS2PubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50128690(4-Hydroxy-7-{2-[2-(3-phenethyloxy-propane-1-sulfon...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to beta1 adrenoceptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5H90PubMed