null

SMILES CS(=O)(=O)c1ccc(cc1)C1=C(CCC1)c1ccc(F)cc1

InChI Key InChIKey=GJGZQTGPOKPFES-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50029614   

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50029614((SC-57666)1-[2-(4-fluorophenyl)-1-cyclopentenyl]-4...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+6nMAssay Description:Compound was evaluated in vitro for the inhibitory activity against constitutive form of human recombinant Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26Z3Q
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The M.S University of Baroda

Curated by ChEMBL
LigandPNGBDBM50029614((SC-57666)1-[2-(4-fluorophenyl)-1-cyclopentenyl]-4...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant human COX-2 expressed in Baculovirus infected sf9 cells using arachidonic acid as substrate preincubated for 10 mins follow...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7DSWPubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50029614((SC-57666)1-[2-(4-fluorophenyl)-1-cyclopentenyl]-4...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+6nMAssay Description:In vitro inhibition of prostaglandin G/H synthase 1.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23N22D2PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The M.S University of Baroda

Curated by ChEMBL
LigandPNGBDBM50029614((SC-57666)1-[2-(4-fluorophenyl)-1-cyclopentenyl]-4...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:In vitro inhibition of prostaglandin G/H synthase 2 (COX-2).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23N22D2PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50029614((SC-57666)1-[2-(4-fluorophenyl)-1-cyclopentenyl]-4...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 (COX-1).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9Q6MPubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50029614((SC-57666)1-[2-(4-fluorophenyl)-1-cyclopentenyl]-4...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5S1GPubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50029614((SC-57666)1-[2-(4-fluorophenyl)-1-cyclopentenyl]-4...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98763PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50029614((SC-57666)1-[2-(4-fluorophenyl)-1-cyclopentenyl]-4...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Concentration (in microM) to inhibit 50% of Prostaglandin G/H synthase 1 (COX-1) and is expressed in IC50.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K936N4PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50029614((SC-57666)1-[2-(4-fluorophenyl)-1-cyclopentenyl]-4...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2FXDPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The M.S University of Baroda

Curated by ChEMBL
LigandPNGBDBM50029614((SC-57666)1-[2-(4-fluorophenyl)-1-cyclopentenyl]-4...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5S1GPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The M.S University of Baroda

Curated by ChEMBL
LigandPNGBDBM50029614((SC-57666)1-[2-(4-fluorophenyl)-1-cyclopentenyl]-4...)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Inhibitory activity of the compound against prostaglandin G/H synthase 2 (COX-2).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9Q6MPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The M.S University of Baroda

Curated by ChEMBL
LigandPNGBDBM50029614((SC-57666)1-[2-(4-fluorophenyl)-1-cyclopentenyl]-4...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Compound was evaluated in vitro for the inhibitory activity against inducible form of human recombinant Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26Z3Q
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The M.S University of Baroda

Curated by ChEMBL
LigandPNGBDBM50029614((SC-57666)1-[2-(4-fluorophenyl)-1-cyclopentenyl]-4...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibitory activity of the compound against human recombinant Prostaglandin G/H synthase 2 expressed in microsomes taken from baculovirus infected Sf...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4VR4
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The M.S University of Baroda

Curated by ChEMBL
LigandPNGBDBM50029614((SC-57666)1-[2-(4-fluorophenyl)-1-cyclopentenyl]-4...)copy SMILEScopy InChI
Affinity DataIC50: 25.7nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2736S4DPubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50029614((SC-57666)1-[2-(4-fluorophenyl)-1-cyclopentenyl]-4...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory activity of the compound against human recombinant Prostaglandin G/H synthase 1 expressed in microsomes taken from baculovirus infected Sf...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4VR4