null

SMILES COc1ccc(CCCn2ncc3c2nc(N)n2nc(nc32)-c2ccco2)cc1

InChI Key InChIKey=AEULVFLPCJOBCE-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 50094037   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Dipartimento di Scienze Farmaceutiche

Curated by ChEMBL
LigandPNGBDBM50094037(2-Furan-2-yl-7-[3-(4-methoxy-phenyl)-propyl]-7H-py...)copy SMILEScopy InChI
Affinity DataKi: >0.0480nMAssay Description:Binding affinity to human adenosine A2a receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V12510PubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Dipartimento di Scienze Farmaceutiche

Curated by ChEMBL
LigandPNGBDBM50094037(2-Furan-2-yl-7-[3-(4-methoxy-phenyl)-propyl]-7H-py...)copy SMILEScopy InChI
Affinity DataKi:  0.0480nMAssay Description:Inhibitory activity against human adenosine A2A receptor expressed in HEK-293 cells by displacement of [3H]-SCH-58,261More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z037C8PubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Dipartimento di Scienze Farmaceutiche

Curated by ChEMBL
LigandPNGBDBM50094037(2-Furan-2-yl-7-[3-(4-methoxy-phenyl)-propyl]-7H-py...)copy SMILEScopy InChI
Affinity DataKi:  0.0480nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8NPSPubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Dipartimento di Scienze Farmaceutiche

Curated by ChEMBL
LigandPNGBDBM50094037(2-Furan-2-yl-7-[3-(4-methoxy-phenyl)-propyl]-7H-py...)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Antagonist activity at human adenosine A2A receptor expressed in Flp-In-CHO cell membrane assessed as inhibition of NECA-induced cAMP accumulation in...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23200R3PubMed
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
University of Milano-Bicocca

Curated by ChEMBL
LigandPNGBDBM50094037(2-Furan-2-yl-7-[3-(4-methoxy-phenyl)-propyl]-7H-py...)copy SMILEScopy InChI
Affinity DataKi:  0.5nMAssay Description:Inhibitory activity against adenosine A2A receptor in rat striatal membranes by displacement of [3H]-SCH-58,261More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z037C8PubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Universit£ di Trieste

Curated by ChEMBL
LigandPNGBDBM50094037(2-Furan-2-yl-7-[3-(4-methoxy-phenyl)-propyl]-7H-py...)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8NPSPubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Dipartimento di Scienze Farmaceutiche

Curated by ChEMBL
LigandPNGBDBM50094037(2-Furan-2-yl-7-[3-(4-methoxy-phenyl)-propyl]-7H-py...)copy SMILEScopy InChI
Affinity DataKi:  4.10nMAssay Description:Displacement of [3H]CGS21680 from human adenosine A2A receptor expressed in HEK293 cells at 10 uMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2902418PubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Dipartimento di Scienze Farmaceutiche

Curated by ChEMBL
LigandPNGBDBM50094037(2-Furan-2-yl-7-[3-(4-methoxy-phenyl)-propyl]-7H-py...)copy SMILEScopy InChI
Affinity DataKi:  4.10nMAssay Description:Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptor expressed in HEK293 cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0P0BPubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Universit£ di Trieste

Curated by ChEMBL
LigandPNGBDBM50094037(2-Furan-2-yl-7-[3-(4-methoxy-phenyl)-propyl]-7H-py...)copy SMILEScopy InChI
Affinity DataKi:  1.11E+3nMAssay Description:Binding affinity to human adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V12510PubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Universit£ di Trieste

Curated by ChEMBL
LigandPNGBDBM50094037(2-Furan-2-yl-7-[3-(4-methoxy-phenyl)-propyl]-7H-py...)copy SMILEScopy InChI
Affinity DataKi:  1.11E+3nMAssay Description:Inhibitory activity against human adenosine A1 receptor expressed in CHO cells by displacement of [3H]-DPCPXMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z037C8PubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
University of Milano-Bicocca

Curated by ChEMBL
LigandPNGBDBM50094037(2-Furan-2-yl-7-[3-(4-methoxy-phenyl)-propyl]-7H-py...)copy SMILEScopy InChI
Affinity DataKi:  1.82E+3nMAssay Description:Displacement of [3H]-DPCPX from adenosine A1 receptor in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z037C8PubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
University of Milano-Bicocca

Curated by ChEMBL
LigandPNGBDBM50094037(2-Furan-2-yl-7-[3-(4-methoxy-phenyl)-propyl]-7H-py...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Inhibitory activity against human adenosine A2B receptor expressed in HEK-293 cells by displacement of [3H]-DPCPXMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z037C8PubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£ di Trieste

Curated by ChEMBL
LigandPNGBDBM50094037(2-Furan-2-yl-7-[3-(4-methoxy-phenyl)-propyl]-7H-py...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8NPSPubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£ di Trieste

Curated by ChEMBL
LigandPNGBDBM50094037(2-Furan-2-yl-7-[3-(4-methoxy-phenyl)-propyl]-7H-py...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]-AB-MECA from human adenosine A3 receptor expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z037C8PubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
University of Milano-Bicocca

Curated by ChEMBL
LigandPNGBDBM50094037(2-Furan-2-yl-7-[3-(4-methoxy-phenyl)-propyl]-7H-py...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Antagonist activity at human adenosine A2B receptor expressed in CHO cells assessed as inhibition of NECA-stimulated adenylyl cyclase activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8NPSPubMed
TargetAdenosine receptor A3(Bos taurus)
Dipartimento di Scienze Farmaceutiche

Curated by ChEMBL
LigandPNGBDBM50094037(2-Furan-2-yl-7-[3-(4-methoxy-phenyl)-propyl]-7H-py...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to bovine adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V12510PubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
University of Milano-Bicocca

Curated by ChEMBL
LigandPNGBDBM50094037(2-Furan-2-yl-7-[3-(4-methoxy-phenyl)-propyl]-7H-py...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human adenosine A2b receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V12510PubMed
TargetAdenosine receptor A3(Rattus norvegicus)
University of Milano-Bicocca

Curated by ChEMBL
LigandPNGBDBM50094037(2-Furan-2-yl-7-[3-(4-methoxy-phenyl)-propyl]-7H-py...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Inhibitory activity against rat adenosine A3 receptor expressed in HEK-293 cells by displacement of [125I]-AB-MECAMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z037C8PubMed
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
University of Milano-Bicocca

Curated by ChEMBL
LigandPNGBDBM50094037(2-Furan-2-yl-7-[3-(4-methoxy-phenyl)-propyl]-7H-py...)copy SMILEScopy InChI
Affinity DataKd:  0.0480nMAssay Description:Binding affinity to adenosine receptor A2a in rat striatumMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P621JPubMed