null
SMILES O[C@@H]1[C@@H](O)[C@@H](Cc2ccccc2)N(Cc2cccc(c2)C(=O)Nc2nc3ccccc3[nH]2)C(=O)N(Cc2cccc(c2)C(=O)Nc2nc3ccccc3[nH]2)[C@@H]1Cc1ccccc1
InChI Key InChIKey=UWSVAGUSMAEUKO-QHQGJXSCSA-N
PDB links: 2 PDB IDs match this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 155
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
DuPont Merck Pharmaceutical Company
DuPont Merck Pharmaceutical Company
Affinity DataKi: 0.0200nM ΔG°: -15.2kcal/molepH: 5.5 T: 2°CAssay Description:Ki values were determined with recombinant single-chain dimeric HIV protease and a fluorescent substrate. The use of single-chain dimeric protease a...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Lindsley F. Kimball Research Institute of The New York Blood Center
Curated by ChEMBL
Lindsley F. Kimball Research Institute of The New York Blood Center
Curated by ChEMBL
Affinity DataKi: 0.0240nMAssay Description:Inhibition of HIV-1 proteaseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Lindsley F. Kimball Research Institute of The New York Blood Center
Curated by ChEMBL
Lindsley F. Kimball Research Institute of The New York Blood Center
Curated by ChEMBL
Affinity DataKi: 0.0240nMAssay Description:Inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Lindsley F. Kimball Research Institute of The New York Blood Center
Curated by ChEMBL
Lindsley F. Kimball Research Institute of The New York Blood Center
Curated by ChEMBL
Affinity DataKi: 0.0240nMAssay Description:Inhibitory activity against HIV proteaseMore data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Merck Pharmaceutical Company
DuPont Merck Pharmaceutical Company
Affinity DataKi: 0.0240nM ΔG°: -15.1kcal/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Lindsley F. Kimball Research Institute of The New York Blood Center
Curated by ChEMBL
Lindsley F. Kimball Research Institute of The New York Blood Center
Curated by ChEMBL
Affinity DataKi: 0.0240nMAssay Description:Binding affinity to inhibit the purified wild-type HIV-1 ProteaseMore data for this Ligand-Target Pair