null
SMILES Fc1ccc(cc1)-n1cc(CCCCN2CCC3(CC2)OCc2ccccc32)c2ccccc12
InChI Key InChIKey=XWAONOGAGZNUSF-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 23 hits for monomerid = 50035105
Affinity DataKi: 0.120nMAssay Description:Displacement of [3H]-DTG from sigma2 receptor in rat liver membranesMore data for this Ligand-Target Pair
TargetSigma intracellular receptor 2(Homo sapiens (Human))
Guangdong Medical University
Curated by ChEMBL
Guangdong Medical University
Curated by ChEMBL
Affinity DataKi: 0.120nMAssay Description:Binding affinity to sigma-2 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.120nMAssay Description:Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membranes incubated for 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails
Affinity DataKi: 11nMAssay Description:In vivo inhibitory activity against Angiotensin I converting enzyme was evaluated in renal hypertensive ratsMore data for this Ligand-Target Pair
In DepthDetails
In DepthDetails
TargetSigma intracellular receptor 2(Homo sapiens (Human))
Guangdong Medical University
Curated by ChEMBL
Guangdong Medical University
Curated by ChEMBL
In DepthDetails
TargetSigma intracellular receptor 2(Homo sapiens (Human))
Guangdong Medical University
Curated by ChEMBL
Guangdong Medical University
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Inhibition of purified human kidney thiopurine methyltransferase (TPMT)More data for this Ligand-Target Pair
In DepthDetails
In DepthDetails
Affinity DataKi: 17nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in quinea pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain cortex membranes incubated for 120 mins by scintillation counting metho...More data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Displacement of [3H](+)pentazocine from sigma 1 receptor in rat brain homogenates without cerebellumMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Binding affinity to sigma 1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Binding affinity to sigma-1 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Binding affinity to sigma-1 opioid receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Binding affinity to sigma-1 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Binding affinity towards sigma receptor binding site 1 using [3H](+)-pentazocineMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Binding affinity towards Dopamine receptor D2 binding site using [3H]spiroperidol.More data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+4nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor binding site using [3H]8-OH-DPAT .More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2A receptor binding site using [3H]ketanserin .More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Displacement of [3H] (+)-pentazocine from sigma 1 receptor in rat liver homogenateMore data for this Ligand-Target Pair
Affinity DataIC50: 0.120nMAssay Description:Binding affinity towards Sigma receptor site 2 in rat brain using [3H]DTG as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Compound was evaluated for the binding affinity towards Sigma receptor type 1 using radioligand ([3H]-(+)- Pentazocine) binding assay.More data for this Ligand-Target Pair