null

SMILES Cc1cccc(c1)N1CC(CO)OC1=O

InChI Key InChIKey=MXUNKHLAEDCYJL-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 29 hits for monomerid = 50110725   

TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Università di Roma La Sapienza

Curated by ChEMBL
LigandPNGBDBM50110725(5-(hydroxymethyl)-3-(3-methylphenyl)-oxazolidin-2-...)copy SMILEScopy InChI
Affinity DataKi:  380nMAssay Description:Inhibtory concentration for rat Monoamine oxidase AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862FZVPubMed
TargetAmine oxidase [flavin-containing] A(Bos taurus)
Universit£ degli Studi di Roma La Sapienza

Curated by ChEMBL
LigandPNGBDBM50110725(5-(hydroxymethyl)-3-(3-methylphenyl)-oxazolidin-2-...)copy SMILEScopy InChI
Affinity DataKi:  380nMAssay Description:Inhibition of bovine brain mitochondrial Monoamine oxidase A (MAO-A) compared to toloxatoneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3F11PubMed
TargetAmine oxidase [flavin-containing] A(Bos taurus)
Universit£ degli Studi di Roma La Sapienza

Curated by ChEMBL
LigandPNGBDBM50110725(5-(hydroxymethyl)-3-(3-methylphenyl)-oxazolidin-2-...)copy SMILEScopy InChI
Affinity DataKi:  380nMAssay Description:Inhibition of bovine brain MAOA using kynuramine as a substrate after 30 mins by spectrofluorometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4C1SPubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM50110725(5-(hydroxymethyl)-3-(3-methylphenyl)-oxazolidin-2-...)copy SMILEScopy InChI
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of MAO-A (unknown origin) by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4TJZPubMed
TargetAmine oxidase [flavin-containing] A(Bos taurus)
Universit£ degli Studi di Roma La Sapienza

Curated by ChEMBL
LigandPNGBDBM50110725(5-(hydroxymethyl)-3-(3-methylphenyl)-oxazolidin-2-...)copy SMILEScopy InChI
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of bovine MAO-A by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542NC3PubMed
TargetAmine oxidase [flavin-containing] B(Bos taurus)
Universit£ degli Studi di Roma La Sapienza

Curated by ChEMBL
LigandPNGBDBM50110725(5-(hydroxymethyl)-3-(3-methylphenyl)-oxazolidin-2-...)copy SMILEScopy InChI
Affinity DataKi:  1.50E+4nMAssay Description:Inhibition of bovine brain mitochondrial Monoamine oxidase B (MAO-B) compared to toloxatoneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3F11PubMed
TargetAmine oxidase [flavin-containing] B(Bos taurus)
Universit£ degli Studi di Roma La Sapienza

Curated by ChEMBL
LigandPNGBDBM50110725(5-(hydroxymethyl)-3-(3-methylphenyl)-oxazolidin-2-...)copy SMILEScopy InChI
Affinity DataKi:  1.50E+4nMAssay Description:Inhibition of bovine brain MAOB using kynuramine as a substrate after 30 mins by spectrofluorometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4C1SPubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Università di Roma La Sapienza

Curated by ChEMBL
LigandPNGBDBM50110725(5-(hydroxymethyl)-3-(3-methylphenyl)-oxazolidin-2-...)copy SMILEScopy InChI
Affinity DataKi:  1.50E+4nMAssay Description:Inhibitory concentration for human Monoamine oxidase BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862FZVPubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM50110725(5-(hydroxymethyl)-3-(3-methylphenyl)-oxazolidin-2-...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Reversible inhibition of recombinant human MAO-A assessed as residual activity using kynuramine as substrate preincubated for 30 mins followed by dia...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0WCTPubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM50110725(5-(hydroxymethyl)-3-(3-methylphenyl)-oxazolidin-2-...)copy SMILEScopy InChI
Affinity DataIC50: 3.92E+3nMAssay Description:Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cell microsomes using kynuramine as substrate after 20 mins by flu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2KM1PubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Università di Roma La Sapienza

Curated by ChEMBL
LigandPNGBDBM50110725(5-(hydroxymethyl)-3-(3-methylphenyl)-oxazolidin-2-...)copy SMILEScopy InChI
Affinity DataIC50: 3.26E+3nMAssay Description:Inhibition of Sprague-Dawley rat brain MAO-A using [14C]5-HT as substrate preincubated for 20 mins followed by substrate addition measured after 5 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29P343FPubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM50110725(5-(hydroxymethyl)-3-(3-methylphenyl)-oxazolidin-2-...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human recombinant MAOA using kynuramine as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3P2RPubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM50110725(5-(hydroxymethyl)-3-(3-methylphenyl)-oxazolidin-2-...)copy SMILEScopy InChI
Affinity DataIC50: 3.92E+3nMAssay Description:Inhibition of recombinant human MAO-A using kynuramine as substrate after 20 mins by fluorescence spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9KQPPubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM50110725(5-(hydroxymethyl)-3-(3-methylphenyl)-oxazolidin-2-...)copy SMILEScopy InChI
Affinity DataIC50: 3.92E+3nMAssay Description:Inhibition of human recombinant MAO-A using kynuramine as substrate incubated for 20 mins by fluorescence spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC06JKPubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM50110725(5-(hydroxymethyl)-3-(3-methylphenyl)-oxazolidin-2-...)copy SMILEScopy InChI
Affinity DataIC50: 3.92E+3nMAssay Description:Inhibition of human recombinant MAO-A expressed in insect cells microsomes assessed as inhibition of 4-hydroxyquinoline formation using kynuramine as...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64NBTPubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM50110725(5-(hydroxymethyl)-3-(3-methylphenyl)-oxazolidin-2-...)copy SMILEScopy InChI
Affinity DataIC50: 3.92E+3nMAssay Description:Inhibition of recombinant human MAOA expressed in insect cell microsomes using kynuramine as substrate measured after 20 mins by fluorescence spectro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD72QDPubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM50110725(5-(hydroxymethyl)-3-(3-methylphenyl)-oxazolidin-2-...)copy SMILEScopy InChI
Affinity DataIC50: 930nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI insect cells using kynuramine as substrate after 20 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7N5DPubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM50110725(5-(hydroxymethyl)-3-(3-methylphenyl)-oxazolidin-2-...)copy SMILEScopy InChI
Affinity DataIC50: 1.64E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB78PTPubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM50110725(5-(hydroxymethyl)-3-(3-methylphenyl)-oxazolidin-2-...)copy SMILEScopy InChI
Affinity DataIC50: 1.64E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q241724GPubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM50110725(5-(hydroxymethyl)-3-(3-methylphenyl)-oxazolidin-2-...)copy SMILEScopy InChI
Affinity DataIC50: 3.92E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27085G5PubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM50110725(5-(hydroxymethyl)-3-(3-methylphenyl)-oxazolidin-2-...)copy SMILEScopy InChI
Affinity DataIC50: 980nMAssay Description:Inhibition of recombinant human MAO-A using kynuramine as substrate incubated for 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0WCTPubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM50110725(5-(hydroxymethyl)-3-(3-methylphenyl)-oxazolidin-2-...)copy SMILEScopy InChI
Affinity DataIC50: 1.78E+3nMAssay Description:Inhibition of recombinant human MAO-A using kynuramine as substrate incubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67K5KPubMed
TargetAmine oxidase [flavin-containing] B(Bos taurus)
Universit£ degli Studi di Roma La Sapienza

Curated by ChEMBL
LigandPNGBDBM50110725(5-(hydroxymethyl)-3-(3-methylphenyl)-oxazolidin-2-...)copy SMILEScopy InChI
Affinity DataIC50: 1.51E+4nMAssay Description:Inhibition of bovine mitochondrial MAOBMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28053T0PubMed
TargetAmine oxidase [flavin-containing] A(Bos taurus)
Universit£ degli Studi di Roma La Sapienza

Curated by ChEMBL
LigandPNGBDBM50110725(5-(hydroxymethyl)-3-(3-methylphenyl)-oxazolidin-2-...)copy SMILEScopy InChI
Affinity DataIC50: 380nMAssay Description:Inhibition of bovine mitochondrial MAOAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28053T0PubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM50110725(5-(hydroxymethyl)-3-(3-methylphenyl)-oxazolidin-2-...)copy SMILEScopy InChI
Affinity DataIC50: 3.92E+3nMAssay Description:Inhibition of recombinant human MAO-A after 20 mins using 50 uM kynuramine as substrate by fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154JWFPubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM50110725(5-(hydroxymethyl)-3-(3-methylphenyl)-oxazolidin-2-...)copy SMILEScopy InChI
Affinity DataIC50: 3.92E+3nMAssay Description:Inhibition of human recombinant MAO-A assessed as kynuramine oxidation to 4-hydroxyquinoline formation by spectrofluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M32XDJPubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM50110725(5-(hydroxymethyl)-3-(3-methylphenyl)-oxazolidin-2-...)copy SMILEScopy InChI
Affinity DataIC50: 3.92E+3nMMore data for this Ligand-Target Pair
In DepthDetails
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM50110725(5-(hydroxymethyl)-3-(3-methylphenyl)-oxazolidin-2-...)copy SMILEScopy InChI
Affinity DataIC50: 3.92E+3nMAssay Description:Inhibition of recombinant human MAO-A using kynuramine as substrate assessed as 4-hydroxyquinoline production after 30 mins by fluorescence spectroph...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93936PubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM50110725(5-(hydroxymethyl)-3-(3-methylphenyl)-oxazolidin-2-...)copy SMILEScopy InChI
Affinity DataIC50: 3.92E+3nMAssay Description:Inhibition of recombinant human MAO-A expressed in insect cells assessed as inhibition of oxidation of kynuramine to 4-hydroxyquinoline after 20 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90B7KPubMed