null
SMILES Cc1c(CCO)sc[n+]1Cc1cnc(C)nc1N
InChI Key InChIKey=JZRWCGZRTZMZEH-UHFFFAOYSA-N
PDB links: 15 PDB IDs match this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50373877
Affinity DataKi: 62nM ΔG°: -9.83kcal/molepH: 7.5 T: 2°CAssay Description:Phenol red (at a concentration of 0.2 mM) has been used as indicator, working at the absorbance maximum of 557 nm, with 10 mM Tris-HCl (pH 7.5) as bu...More data for this Ligand-Target Pair
Affinity DataKi: 85nM ΔG°: -9.64kcal/molepH: 7.5 T: 2°CAssay Description:Phenol red (at a concentration of 0.2 mM) has been used as indicator, working at the absorbance maximum of 557 nm, with 10 mM Tris-HCl (pH 7.5) as bu...More data for this Ligand-Target Pair
Affinity DataKi: 380nM ΔG°: -8.75kcal/molepH: 7.5 T: 2°CAssay Description:Phenol red (at a concentration of 0.2 mM) has been used as indicator, working at the absorbance maximum of 557 nm, with 10 mM Tris-HCl (pH 7.5) as bu...More data for this Ligand-Target Pair
Affinity DataKi: 3.30E+5nMpH: 8.25Assay Description:Noncompetitive inhibition of electric eel AChE using acetylthiocholine chloride as substrate at pH 8.25 by Michaelis-Menten plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3.90E+5nMpH: 8.25Assay Description:Competitive inhibition of electric eel AChE using acetylthiocholine chloride as substrate at pH 8.25 by Michaelis-Menten plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 4.30E+5nMpH: 7.0Assay Description:Competitive inhibition of electric eel AChE using acetylthiocholine chloride as substrate at pH 7 by Michaelis-Menten plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 5.70E+5nMpH: 7.0Assay Description:Noncompetitive inhibition of electric eel AChE using acetylthiocholine chloride as substrate at pH 7 by Michaelis-Menten plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 6.46E+5nMAssay Description:TP_TRANSPORTER: inhibition of TEA uptake in OCT2-expressing MDCK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 7.36E+5nMAssay Description:TP_TRANSPORTER: inhibition of TEA uptake in OCT1-expressing MDCK cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of recombinant Homo sapiens (human) Hsp90 alpha ATPase activity assessed as inorganic phosphate release by malachite green colorimetric me...More data for this Ligand-Target Pair
Affinity DataKd: 6.80E+6nMAssay Description:Inhibition of apo-transketolaseMore data for this Ligand-Target Pair
TargetSolute carrier family 22 member 1(Homo sapiens (Human))
University of California
Curated by ChEMBL
University of California
Curated by ChEMBL
Affinity DataIC50: 4.35E+6nMAssay Description:Inhibition of human OCT1 expressed in HEK293 cells assessed as decrease in uptake of MPP+ after 1 minMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKd: 3.80nMAssay Description:the kd for ThOH, ThMP and ThDP were determined using titration experiments in which the change in the intrinsic protein fluorescence was monitored as...More data for this Ligand-Target Pair