null

SMILES N[C@@H](Cc1ccc(O)cc1)C(O)=O

InChI Key InChIKey=OUYCCCASQSFEME-QMMMGPOBSA-N

PDB links: 23 PDB IDs match this monomer. 44 PDB IDs contain this monomer as substructures. 44 PDB IDs contain inhibitors having a similarity of 90% to this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 18129   

TargetTubulin--tyrosine ligase(Homo sapiens (Human))
Binghamton University

LigandPNGBDBM18129((2S)-2-amino-3-(4-hydroxyphenyl)propanoic acid | L...)copy SMILEScopy InChI
Affinity DataKi:  2.50E+4nM ΔG°:  -6.53kcal/molepH: 6.8 T: 2°CAssay Description:Inhibition of [3H]-L-tyrosine incorporation into tubulin by enzyme tubulin tyrosine ligase (TTL).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7DM1PubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
CHINA PHARMACEUTICAL UNIVERSITY

US Patent
LigandPNGBDBM18129((2S)-2-amino-3-(4-hydroxyphenyl)propanoic acid | L...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+4nMAssay Description:11.1 Preparation of Reagents and Standard Solutions(1) 75 mM phosphate buffer (PB, pH 7.4): containing KH2PO4 0.0956 g, K2HPO4 0.6946 g, EDTA 1.862 m...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959MQDUS Patent
TargetLarge neutral amino acids transporter small subunit 1(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM18129((2S)-2-amino-3-(4-hydroxyphenyl)propanoic acid | L...)copy SMILEScopy InChI
Affinity DataIC50: 6.80E+4nMAssay Description:Cis-inhibition of human LAT1 expressed in TREx HEK293 cells at 200 uM assessed as inhibition of [3H]-gabapentin uptake preincubated for 3 mins at 37 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8J66PubMed