null
SMILES N[C@@H](Cc1ccc(O)cc1)C(O)=O
InChI Key InChIKey=OUYCCCASQSFEME-QMMMGPOBSA-N
PDB links: 23 PDB IDs match this monomer. 44 PDB IDs contain this monomer as substructures. 44 PDB IDs contain inhibitors having a similarity of 90% to this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 18129
Affinity DataKi: 2.50E+4nM ΔG°: -6.53kcal/molepH: 6.8 T: 2°CAssay Description:Inhibition of [3H]-L-tyrosine incorporation into tubulin by enzyme tubulin tyrosine ligase (TTL).More data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+4nMAssay Description:11.1 Preparation of Reagents and Standard Solutions(1) 75 mM phosphate buffer (PB, pH 7.4): containing KH2PO4 0.0956 g, K2HPO4 0.6946 g, EDTA 1.862 m...More data for this Ligand-Target Pair
TargetLarge neutral amino acids transporter small subunit 1(Homo sapiens (Human))
University of California
Curated by ChEMBL
University of California
Curated by ChEMBL
Affinity DataIC50: 6.80E+4nMAssay Description:Cis-inhibition of human LAT1 expressed in TREx HEK293 cells at 200 uM assessed as inhibition of [3H]-gabapentin uptake preincubated for 3 mins at 37 ...More data for this Ligand-Target Pair