null

SMILES CCCCNc1ncc2c(cn([C@H]3CC[C@H](O)CC3)c2n1)-c1ccc(cc1)S(=O)(=O)N1CCOCC1

InChI Key InChIKey=NDWOEUVAOGUXGP-MEMLXQNLSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 350864   

TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
The University of North Carolina at Chapel Hill

US Patent
LigandPNGBDBM350864(UNC1666A | US10004755, Compound UNC1666A | US97956...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:The ectopic expression of Mer receptor tyrosine kinase (Mer) has been identified as a tumor cell survival gene product in Acute Lymphoblastic Leukemi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB553DUS Patent
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
The University of North Carolina at Chapel Hill

US Patent
LigandPNGBDBM350864(UNC1666A | US10004755, Compound UNC1666A | US97956...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition constants of MerTK, Flt3, Tyro3 and Axl kinase activity by an active compound as described herein is determined at the Km for ATP using a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26H4KR2US Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))TBA
LigandPNGBDBM350864(UNC1666A | US10004755, Compound UNC1666A | US97956...)copy SMILEScopy InChI
Ligand InfoPC cidPC sid
In DepthDetails
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
NIH

LigandPNGBDBM350864(UNC1666A | US10004755, Compound UNC1666A | US97956...)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition constants of MerTK, Flt3, Tyro3 and Axl kinase activity by an active compound as described herein is determined at the Km for ATP using a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26H4KR2US Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))TBA
LigandPNGBDBM350864(UNC1666A | US10004755, Compound UNC1666A | US97956...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Inhibition constants of MerTK, Flt3, Tyro3 and Axl kinase activity by an active compound as described herein is determined at the Km for ATP using a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26H4KR2US Patent
TargetTyrosine-protein kinase receptor TYRO3(Homo sapiens (Human))
NIH

LigandPNGBDBM350864(UNC1666A | US10004755, Compound UNC1666A | US97956...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition constants of MerTK, Flt3, Tyro3 and Axl kinase activity by an active compound as described herein is determined at the Km for ATP using a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26H4KR2US Patent