null

SMILES CCC(=O)C1C2CCC(CC1c1ccc3ccccc3c1)N2C

InChI Key InChIKey=WJVLEIDMFWNIAA-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50041293   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041293(1-(8-Methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]...)copy SMILEScopy InChI
Affinity DataKi:  0.121nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transport sites in rat frontal cortex membranes.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TH8NBMPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by PDSP Ki Database
LigandPNGBDBM50041293(1-(8-Methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]...)copy SMILEScopy InChI
Affinity DataKi:  0.140nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H993QFPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041293(1-(8-Methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]...)copy SMILEScopy InChI
Affinity DataKi:  0.390nMAssay Description:Displacement of [3H]-paroxetine from Serotonin transporter of rat frontal cortex membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69HP1PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041293(1-(8-Methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]...)copy SMILEScopy InChI
Affinity DataKi:  0.394nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transport sites in rat frontal cortex membranes.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TH8NBMPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by PDSP Ki Database
LigandPNGBDBM50041293(1-(8-Methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]...)copy SMILEScopy InChI
Affinity DataKi:  0.650nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H993QFPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by PDSP Ki Database
LigandPNGBDBM50041293(1-(8-Methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]...)copy SMILEScopy InChI
Affinity DataKi:  1.03nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H993QFPubMed
TargetTransporter(Rattus norvegicus)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50041293(1-(8-Methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]...)copy SMILEScopy InChI
Affinity DataKi:  2.90nMAssay Description:Displacement of [3H]-nisoxatine from Norepinephrine transporter of rat forebrain membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69HP1PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041293(1-(8-Methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]...)copy SMILEScopy InChI
Affinity DataKi:  16.4nMAssay Description:Affinity for the displacement of [3H]-paroxetine binding to serotonin transporter (SERT) in rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H1318RPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041293(1-(8-Methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]...)copy SMILEScopy InChI
Affinity DataKi:  16.4nMAssay Description:Affinity for the displacement of [3H]-paroxetine binding to serotonin transporter (SERT) in rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H1318RPubMed
TargetTransporter(Rattus norvegicus)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50041293(1-(8-Methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]...)copy SMILEScopy InChI
Affinity DataKi:  68nMAssay Description:Affinity for the displacement of [3H]-paroxetine binding to norepinephrine transporter (NET) in rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H1318RPubMed
TargetTransporter(Rattus norvegicus)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50041293(1-(8-Methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]...)copy SMILEScopy InChI
Affinity DataKi:  68nMAssay Description:Affinity for the displacement of [3H]-paroxetine binding to norepinephrine transporter (NET) in rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H1318RPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by PDSP Ki Database
LigandPNGBDBM50041293(1-(8-Methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]...)copy SMILEScopy InChI
Affinity DataIC50: 0.115nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TH8NBMPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by PDSP Ki Database
LigandPNGBDBM50041293(1-(8-Methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]...)copy SMILEScopy InChI
Affinity DataIC50: 2.51nMAssay Description:Inhibitory activity in displacing [125I]- RTI-55 binding to dopamine transporter in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H1318RPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by PDSP Ki Database
LigandPNGBDBM50041293(1-(8-Methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]...)copy SMILEScopy InChI
Affinity DataIC50: 0.0430nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TH8NBMPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by PDSP Ki Database
LigandPNGBDBM50041293(1-(8-Methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]...)copy SMILEScopy InChI
Affinity DataIC50: 0.120nMAssay Description:Displacement of [125I]-RTI-55 from dopamine transporter of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69HP1PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by PDSP Ki Database
LigandPNGBDBM50041293(1-(8-Methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]...)copy SMILEScopy InChI
Affinity DataIC50: 2.51nMAssay Description:Inhibitory activity in displacing [125I]- RTI-55 binding to dopamine transporter in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H1318RPubMed