null

SMILES COc1ccc(cc1)C(CN(C)C)C1(O)CCCCC1

InChI Key InChIKey=PNVNVHUZROJLTJ-UHFFFAOYSA-N

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 226 hits for monomerid = 82071   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Laboratories, Inc.

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  0.100nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J69CPPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Laboratories, Inc.

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  0.190nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J69CPPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Laboratories, Inc.

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  0.210nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J69CPPubMed
TargetNorepinephrine transporter(RAT)
Wyeth Laboratories, Inc.

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  0.640nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J69CPPubMed
TargetNorepinephrine transporter(RAT)
Wyeth Laboratories, Inc.

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  0.760nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J69CPPubMed
TargetNorepinephrine transporter(RAT)
Wyeth Laboratories, Inc.

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  1.26nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3JQXPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wyeth Laboratories, Inc.

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  2.80nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J69CPPubMed
TargetNorepinephrine transporter(RAT)
Wyeth Laboratories, Inc.

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  3.14nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J69CPPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  7.5nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25Q4TMXPubMedDrugBank
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  7.80nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64GMBPubMedDrugBank
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  8.90nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69H3DPubMedDrugBank
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Laboratories, Inc.

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  19nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25Q4TMXPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Laboratories, Inc.

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  24.5nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7FVWPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Laboratories, Inc.

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  37nMAssay Description:Inhibition of [3H]5-HT reuptake into rat frontal cortex synaptosomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F76D26PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  39nMAssay Description:Binding affinity to human SERT expressed in HEK293 cells after 60 mins in presence of [3H]imipramine by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7K8MPubMedDrugBank
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Laboratories, Inc.

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  52nMAssay Description:Binding affinity to the serotonin transporter (SERT) measured by displacement of [3H]paroxetine in male wistar ratsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8TMNPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Laboratories, Inc.

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  74nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3JQXPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Laboratories, Inc.

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  74nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q279436BPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  75.9nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7FVWPubMedDrugBank
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  82nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ318RPubMedDrugBank
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  82nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M648WPubMedDrugBank
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Laboratories, Inc.

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  90nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J69CPPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  102nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25Q4TMXPubMedDrugBank
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Laboratories, Inc.

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  109nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J69CPPubMed
TargetTransporter(Rattus norvegicus)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  138nMAssay Description:Inhibition of [3H]- NE reuptake into rat hippocampal synaptosomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F76D26PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Laboratories, Inc.

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  138nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M648WPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Laboratories, Inc.

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  140nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J69CPPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  145nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64GMBPubMedDrugBank
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Laboratories, Inc.

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  210nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ02CPPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Biocon Bristol-Myers Squibb R&D Centre

Curated by ChEMBL
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  210nMAssay Description:Binding affinity to human NET expressed in HEK293 cells after 60 mins in presence of [3H]imipramine by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7K8MPubMedDrugBank
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wyeth Laboratories, Inc.

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  360nMAssay Description:Inhibition of [3H]- DA reuptake into rat striatal synaptosomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F76D26PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Biocon Bristol-Myers Squibb R&D Centre

Curated by ChEMBL
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  385nMAssay Description:Displacement of [3H]nisoxetine from human norepinephrine transporter expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16PBPubMedDrugBank
TargetNorepinephrine transporter(RAT)
Wyeth Laboratories, Inc.

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  640nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ02CPPubMed
TargetTransporter(Rattus norvegicus)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  719nMAssay Description:Binding affinity against norepinephrine transporter (NET) by displacement of [3H]nisoxetine in male wistar ratsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8TMNPubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Lilly Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M648WPubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Lilly Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M648WPubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Lilly Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M648WPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Rattus norvegicus (Rat))
Lilly Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M648WPubMed
TargetCalcium-activated potassium channel subunit beta-1(RAT)
Lilly Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M648WPubMed
TargetProtein kinase C alpha type(MOUSE)
Lilly Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M648WPubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Lilly Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M648WPubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Lilly Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M648WPubMed
TargetSodium channel protein type 1 subunit alpha(Rattus norvegicus)
Lilly Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M648WPubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Lilly Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M648WPubMed
TargetSomatostatin(RAT)
Lilly Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M648WPubMed
TargetNorepinephrine transporter(RAT)
Wyeth Laboratories, Inc.

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7FVWPubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Lilly Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M648WPubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Lilly Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M648WPubMed
TargetAdenosine receptor A2b(BOVINE)
Lilly Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M648WPubMed
TargetSodium/nucleoside cotransporter(RAT)
Lilly Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M648WPubMed
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