null

SMILES CC(=N)N1CCC(CC1)Oc1ccc(cc1)N(Cc1ccc2ccc(cc2c1)C(N)=N)S(=O)(=O)CC(O)=O

InChI Key InChIKey=NPBKHEMDWREFJJ-UHFFFAOYSA-N

PDB links: 1 PDB ID matches this monomer.

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Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50084617   

TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50084617(((7-carbamimidoyl-naphthalen-2-ylmethyl)-{4-[1-(1-...)copy SMILEScopy InChI
Affinity DataKi:  1.30nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5VBBPubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50084617(((7-carbamimidoyl-naphthalen-2-ylmethyl)-{4-[1-(1-...)copy SMILEScopy InChI
Affinity DataKi:  1.30nMAssay Description:Binding affinity against Coagulation factor XChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JD4XH4PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50084617(((7-carbamimidoyl-naphthalen-2-ylmethyl)-{4-[1-(1-...)copy SMILEScopy InChI
Affinity DataKi:  2.30nMAssay Description:Inhibitory concentration against human Coagulation factor Xa (fXa)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319V5WPubMed
TargetSerine protease 1(Bos taurus (bovine))
Protherics Molecular Design

Curated by ChEMBL
LigandPNGBDBM50084617(((7-carbamimidoyl-naphthalen-2-ylmethyl)-{4-[1-(1-...)copy SMILEScopy InChI
Affinity DataKi:  159nMAssay Description:Inhibitory concentration against bovine trypsinMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Protherics Molecular Design

Curated by ChEMBL
LigandPNGBDBM50084617(((7-carbamimidoyl-naphthalen-2-ylmethyl)-{4-[1-(1-...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Inhibitory concentration against thrombin.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319V5WPubMed
TargetProthrombin(Homo sapiens (Human))
Protherics Molecular Design

Curated by ChEMBL
LigandPNGBDBM50084617(((7-carbamimidoyl-naphthalen-2-ylmethyl)-{4-[1-(1-...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5VBBPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Portola Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50084617(((7-carbamimidoyl-naphthalen-2-ylmethyl)-{4-[1-(1-...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]dofetilide from human ERG potassium channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2X05PubMed
TargetProthrombin(Homo sapiens (Human))
Protherics Molecular Design

Curated by ChEMBL
LigandPNGBDBM50084617(((7-carbamimidoyl-naphthalen-2-ylmethyl)-{4-[1-(1-...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity against Thrombin.Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JD4XH4PubMed
TargetCoagulation factor X(Mus musculus)TBA
LigandPNGBDBM50084617(((7-carbamimidoyl-naphthalen-2-ylmethyl)-{4-[1-(1-...)copy SMILEScopy InChI
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52TMMPubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50084617(((7-carbamimidoyl-naphthalen-2-ylmethyl)-{4-[1-(1-...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibitory concentration of the compound to factor XaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DB816XPubMed
TargetAnionic trypsin-2(Rattus norvegicus)
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50084617(((7-carbamimidoyl-naphthalen-2-ylmethyl)-{4-[1-(1-...)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibitory concentration of the compound against trypsinMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DB816XPubMed
TargetProthrombin(Homo sapiens (Human))
Protherics Molecular Design

Curated by ChEMBL
LigandPNGBDBM50084617(((7-carbamimidoyl-naphthalen-2-ylmethyl)-{4-[1-(1-...)copy SMILEScopy InChI
Affinity DataIC50: 7.70nMAssay Description:Inhibitory concentration against prothrombinChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JD4XH4PubMed