null

SMILES CC(N)Cc1ccccc1

InChI Key InChIKey=KWTSXDURSIMDCE-UHFFFAOYSA-N

PDB links: 4 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 55 hits for monomerid = 50005246   

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
National Institute on Drug Abuse

Curated by PDSP Ki Database
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataKi:  7.10nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3BVJPubMedDrugBank
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
National Institute on Drug Abuse

Curated by PDSP Ki Database
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataKi:  24.8nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3BVJPubMedDrugBank
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
NIH

Curated by PDSP Ki Database
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataKi:  34nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9GT3PubMed
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataKi:  38.9nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9GT3PubMed
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataKi:  58nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9TR3PubMed
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataKi:  59nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9TR3PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
National Institute on Drug Abuse

Curated by PDSP Ki Database
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataKi:  116nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NG4P5CPubMedDrugBank
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
National Institute on Drug Abuse

Curated by PDSP Ki Database
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataKi:  190nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NG4P5CPubMedDrugBank
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
NIH

Curated by PDSP Ki Database
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataKi:  400nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9TR3PubMed
TargetAlpha-2C adrenergic receptor(RAT)
University of California

Curated by PDSP Ki Database
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataKi:  992nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F18X7BPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Novo Industri A/S

Curated by PDSP Ki Database
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9TR3PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
NIH

Curated by PDSP Ki Database
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1JH0PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Novo Industri A/S

Curated by PDSP Ki Database
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9TR3PubMed
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1JH0PubMed
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
TBA

Curated by PDSP Ki Database
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataKi:  1.60E+3nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4PFZPubMed
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
TBA

Curated by PDSP Ki Database
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataKi:  2.20E+3nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4PFZPubMed
TargetAlpha-2C adrenergic receptor(RAT)
University of California

Curated by PDSP Ki Database
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataKi:  2.41E+3nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F18X7BPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
NIH

Curated by PDSP Ki Database
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataKi:  2.90E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9TR3PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Novo Industri A/S

Curated by PDSP Ki Database
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataKi:  3.83E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9GT3PubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
SRI International

Curated by PDSP Ki Database
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataKi:  6.61E+3nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3BH2PubMed
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataKi:  7.66E+3nMAssay Description:Evaluated for binding affinity towards rat cortical membranes at 5-hydroxytryptamine 1 receptor binding site by using [3H]-5-HT as a radioligand.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4BS7PubMed
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataKi:  7.66E+3nMAssay Description:Binding affinity for 5-hydroxytryptamine 1 receptor of rat prefrontal cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KP84CDPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Novo Industri A/S

Curated by PDSP Ki Database
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1JH0PubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
SRI International

Curated by PDSP Ki Database
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3BH2PubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
SRI International

Curated by PDSP Ki Database
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3BH2PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
SRI International

Curated by PDSP Ki Database
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3BH2PubMedDrugBank
TargetD(1A) dopamine receptor(Homo sapiens (Human))
SRI International

Curated by PDSP Ki Database
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3BH2PubMed
Target5-hydroxytryptamine receptor 3A(Mus musculus (house mouse))
SRI International

Curated by PDSP Ki Database
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3BH2PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
National Institute on Drug Abuse

Curated by PDSP Ki Database
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NG4P5CPubMedDrugBank
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
TBA

Curated by PDSP Ki Database
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4PFZPubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
TBA

Curated by PDSP Ki Database
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZK5F5PPubMedDrugBank
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
TBA

Curated by PDSP Ki Database
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZK5F5PPubMedDrugBank
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM284NPubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
SRI International

Curated by PDSP Ki Database
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3BH2PubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
SRI International

Curated by PDSP Ki Database
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]ketanserin from rat 5HT2A expressed in mouse NIH/3T3 cell membranes after 30 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5HWMPubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for binding affinity towards 5-hydroxytryptamine 2 (5-hydroxytryptamine-2) receptor from frontal cortical regions of male Sprague...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4BV4PubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
SRI International

Curated by PDSP Ki Database
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for binding affinity towards 5-hydroxytryptamine 1C receptor from frontal cortical regions of male Sprague-Dawley rat homogenates...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4BV4PubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
SRI International

Curated by PDSP Ki Database
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-ketanserin from NIH3T3 cells stably expressing rat 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NZ86VWPubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
SRI International

Curated by PDSP Ki Database
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-mesulergine from A9 cells stably expressing rat 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NZ86VWPubMed
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
TBA

Curated by PDSP Ki Database
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataKi:  1.20E+4nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4PFZPubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
University of Chile

Curated by ChEMBL
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataKi:  1.22E+4nMAssay Description:Inhibition of MAOA in rat brain mitochondriaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5GZ3PubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataKi:  4.30E+4nMAssay Description:Binding affinity to rat cortical membranes at 5-hydroxytryptamine 2 (5-HT2) receptor using [3H]KET as a radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4BS7PubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataKi:  4.30E+4nMAssay Description:Displacement of [3H]ketanserin from rat prefrontal cortex 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KP84CDPubMed
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity towards sigma opioid receptor was determined in rat cerebral homogenate using [3H]haloperidol as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28C9WV8PubMed
TargetPhenylethanolamine N-methyltransferase(Bos taurus (bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataKi:  7.40E+5nMAssay Description:Inhibitory activity against bovine adrenal norepinephrine N-methyl-transferase was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S46SJ3PubMed
TargetPhenylethanolamine N-methyltransferase(Bos taurus (bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataKi:  7.40E+5nMAssay Description:Inhibitory activity against Norepinephrine N-methyltransferase of bovine adrenal glandsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22V2F57PubMed
TargetPhenylethanolamine N-methyltransferase(Bos taurus (bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataKi:  7.40E+5nMAssay Description:The inhibitory constant(Ki) value for Norepinephrine N-methyltransferase was calculatedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z31XPVPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
NIH

Curated by PDSP Ki Database
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataIC50: 960nMAssay Description:Inhibition of [3H]dopamine uptake at dopamine transporter expressed in rat striatal homogenate after 5 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FN17RBPubMed
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of 5-HT transporter in NMRI albino mouse brain assessed as [3H]5-HT accumulation in hypothalamus after 5 minsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P270P4PubMed
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of noradrenaline transporter in NMRI albino mouse brain assessed as [3H]NA accumulation in hypothalamus after 5 minsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P270P4PubMed
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