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SMILES Oc1ccc2cc(oc2c1)-c1cc(O)cc(O)c1

InChI Key InChIKey=LHPRYOJTASOZGJ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50250915   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50250915(CHEMBL512578 | moracin M)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human PDE5A1 catalytic domain (535 to 860) expressed in Escherichia coli BL21 using [3H]-cAMP/[3H]-cGMP after 15 mins by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63NZMPubMed
TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Chungbuk National University

Curated by ChEMBL
LigandPNGBDBM50250915(CHEMBL512578 | moracin M)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenylbutyrate as substrate assessed as formation of p-nitrophenol preincubated for 15 mins foll...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0W7BPubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50250915(CHEMBL512578 | moracin M)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38TGVPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50250915(CHEMBL512578 | moracin M)copy SMILEScopy InChI
Affinity DataIC50: 2.23E+4nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38TGVPubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50250915(CHEMBL512578 | moracin M)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE9A2 catalytic domain (181 to 506) expressed in Escherichia coli BL21 using [3H]-cAMP/[3H]-cGMP after 15 mins by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63NZMPubMed
TargetTyrosinase(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50250915(CHEMBL512578 | moracin M)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of tyrosinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN77C2PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50250915(CHEMBL512578 | moracin M)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of human PDE4B2 catalytic domain and UCR2 (92 to 521) expressed in Escherichia coli BL21 using [3H]-cAMP/[3H]-cGMP after 15 mins by liquid...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63NZMPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Sun Yat-sen University

Curated by ChEMBL
LigandPNGBDBM50250915(CHEMBL512578 | moracin M)copy SMILEScopy InChI
Affinity DataIC50: 2.91E+3nMAssay Description:Inhibition of human PDE4D using 3H-cAMP as substrate after 15 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9MZJPubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Korean Research Institute of Biosciences and Biotechnology

Curated by ChEMBL
LigandPNGBDBM50250915(CHEMBL512578 | moracin M)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of hypoxia-induced HIF1alpha protein accumulation in human Hep3B cells treated for 30 mins measured after 12 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27947GKPubMed
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Korean Research Institute of Biosciences and Biotechnology

Curated by ChEMBL
LigandPNGBDBM50250915(CHEMBL512578 | moracin M)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of hypoxia-induced HIF1 activation in human Hep3B cells by pGL3-HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27947GKPubMed
TargetTyrosinase(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50250915(CHEMBL512578 | moracin M)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of tyrosinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN77C2PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Sun Yat-sen University

Curated by ChEMBL
LigandPNGBDBM50250915(CHEMBL512578 | moracin M)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human PDE4D2 catalytic domain (86 to 413) expressed in Escherichia coli BL21 using [3H]-cAMP/[3H]-cGMP after 15 mins by liquid scintill...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63NZMPubMed