null

SMILES NCc1ccccc1

InChI Key InChIKey=WGQKYBSKWIADBV-UHFFFAOYSA-N

PDB links: 18 PDB IDs match this monomer. 1385 PDB IDs contain this monomer as substructures. 1385 PDB IDs contain inhibitors having a similarity of 90% to this monomer.

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Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 10999   

LigandPNGBDBM10999(Benzenemethanamine | Bn-NH2 | CHEMBL522 | benzylam...)copy SMILEScopy InChI
Affinity DataKi:  9.10E+3nMAssay Description:Inhibition of [3H]clonidine binding to the rat alpha-2-adrenoceptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26Q20F9PubMed
TargetPhenylethanolamine N-methyltransferase(Bos taurus (bovine))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM10999(Benzenemethanamine | Bn-NH2 | CHEMBL522 | benzylam...)copy SMILEScopy InChI
Affinity DataKi:  2.35E+4nMAssay Description:Inhibitory activity against bovine adrenal phenylethanolamine N-methyl-transferase (PNMT)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26Q20F9PubMed
TargetPhenylethanolamine N-methyltransferase(Bos taurus (bovine))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM10999(Benzenemethanamine | Bn-NH2 | CHEMBL522 | benzylam...)copy SMILEScopy InChI
Affinity DataKi:  1.70E+5nMAssay Description:Inhibition of bovine PNMT by radiochemical assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B312RPubMed
TargetPhenylethanolamine N-methyltransferase(Bos taurus (bovine))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM10999(Benzenemethanamine | Bn-NH2 | CHEMBL522 | benzylam...)copy SMILEScopy InChI
Affinity DataKi:  1.79E+5nMAssay Description:In vitro for inhibition of Phenylethanolamine N-Methyltransferase (PNMT)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM28RQPubMed
TargetSerine protease 1(Homo sapiens (Human))
Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM10999(Benzenemethanamine | Bn-NH2 | CHEMBL522 | benzylam...)copy SMILEScopy InChI
Affinity DataKi:  3.00E+8nMAssay Description:The compound was tested for inhibition of the proteolytic enzyme trypsin.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2930VD5PubMed
TargetCytochrome P450 130(Mycobacterium tuberculosis)
University of California, San Francisco

LigandPNGBDBM10999(Benzenemethanamine | Bn-NH2 | CHEMBL522 | benzylam...)copy SMILEScopy InChI
Affinity DataKd:  1.00E+7nMAssay Description:Binding assay using CYP130, CYP130 (G234) or CYP142.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR1WVCPubMed
TargetSteroid C26-monooxygenase(Mycobacterium tuberculosis)
University of California, San Francisco

LigandPNGBDBM10999(Benzenemethanamine | Bn-NH2 | CHEMBL522 | benzylam...)copy SMILEScopy InChI
Affinity DataKd:  100nMAssay Description:Binding assay using CYP130, CYP130 (G234) or CYP142.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR1WVCPubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
PharmAkea Inc.

Curated by ChEMBL
LigandPNGBDBM10999(Benzenemethanamine | Bn-NH2 | CHEMBL522 | benzylam...)copy SMILEScopy InChI
Affinity DataIC50: 6.47E+4nMAssay Description:Inhibition of full length recombinant human LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542QV6PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM10999(Benzenemethanamine | Bn-NH2 | CHEMBL522 | benzylam...)copy SMILEScopy InChI
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
In DepthDetails
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM10999(Benzenemethanamine | Bn-NH2 | CHEMBL522 | benzylam...)copy SMILEScopy InChI
Affinity DataIC50: 61nMMore data for this Ligand-Target Pair
In DepthDetails
TargetUrease subunit alpha(Helicobacter pylori ATCC43504)
Wuhan Textile University

LigandPNGBDBM10999(Benzenemethanamine | Bn-NH2 | CHEMBL522 | benzylam...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMpH: 7.4 T: 2°CAssay Description:Briefly, 50 mL broth cultures (2.0 × 10^8 CFU/mL) were centrifuged (5000g, 4°C)to collect the bacteria, and after washing twice with phosph...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445KC3PubMed
TargetCytochrome P450 130(Mycobacterium tuberculosis)
University of California, San Francisco

LigandPNGBDBM10999(Benzenemethanamine | Bn-NH2 | CHEMBL522 | benzylam...)copy SMILEScopy InChI
Affinity DataKd:  9.99E+6nMAssay Description:Binding assay using CYP130, CYP130 (G234) or CYP142.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR1WVCPubMed