null
SMILES NCc1ccccc1
InChI Key InChIKey=WGQKYBSKWIADBV-UHFFFAOYSA-N
PDB links: 18 PDB IDs match this monomer. 1385 PDB IDs contain this monomer as substructures. 1385 PDB IDs contain inhibitors having a similarity of 90% to this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 10999
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
University of Kansas
Curated by ChEMBL
University of Kansas
Curated by ChEMBL
Affinity DataKi: 9.10E+3nMAssay Description:Inhibition of [3H]clonidine binding to the rat alpha-2-adrenoceptorMore data for this Ligand-Target Pair
TargetPhenylethanolamine N-methyltransferase(Bos taurus (bovine))
University of Kansas
Curated by ChEMBL
University of Kansas
Curated by ChEMBL
Affinity DataKi: 2.35E+4nMAssay Description:Inhibitory activity against bovine adrenal phenylethanolamine N-methyl-transferase (PNMT)More data for this Ligand-Target Pair
TargetPhenylethanolamine N-methyltransferase(Bos taurus (bovine))
University of Kansas
Curated by ChEMBL
University of Kansas
Curated by ChEMBL
Affinity DataKi: 1.70E+5nMAssay Description:Inhibition of bovine PNMT by radiochemical assayMore data for this Ligand-Target Pair
TargetPhenylethanolamine N-methyltransferase(Bos taurus (bovine))
University of Kansas
Curated by ChEMBL
University of Kansas
Curated by ChEMBL
Affinity DataKi: 1.79E+5nMAssay Description:In vitro for inhibition of Phenylethanolamine N-Methyltransferase (PNMT)More data for this Ligand-Target Pair
Affinity DataKi: 3.00E+8nMAssay Description:The compound was tested for inhibition of the proteolytic enzyme trypsin.More data for this Ligand-Target Pair
Affinity DataKd: 1.00E+7nMAssay Description:Binding assay using CYP130, CYP130 (G234) or CYP142.More data for this Ligand-Target Pair
Affinity DataKd: 100nMAssay Description:Binding assay using CYP130, CYP130 (G234) or CYP142.More data for this Ligand-Target Pair
Affinity DataIC50: 6.47E+4nMAssay Description:Inhibition of full length recombinant human LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated...More data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
B.MOADDrugBankGoogleScholar
UniProtKB/SwissProtUniProtKB/TrEMBL
B.MOADDrugBankGoogleScholar
In DepthDetails
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
B.MOADDrugBankGoogleScholar
UniProtKB/SwissProtUniProtKB/TrEMBL
B.MOADDrugBankGoogleScholar
In DepthDetails
Affinity DataIC50: 1.00E+5nMpH: 7.4 T: 2°CAssay Description:Briefly, 50 mL broth cultures (2.0 × 10^8 CFU/mL) were centrifuged (5000g, 4°C)to collect the bacteria, and after washing twice with phosph...More data for this Ligand-Target Pair
Affinity DataKd: 9.99E+6nMAssay Description:Binding assay using CYP130, CYP130 (G234) or CYP142.More data for this Ligand-Target Pair